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CBS 抗体 (N-Term)

Name: CBS 抗体 (N-Term)
SKU: ABIN1881141
Availability: OutOfStock

CBS 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB22961 unconjugated

Western blot analysis of CBS Antibody (N-term) (ABIN1881141 and ABIN2841140) in mouse kidney tissue and Ramos cell line lysates (35 μg/lane). (CBS 抗体 (N-Term))

Confocal immunofluorescent analysis of CBS Antibody (N-term) (ABIN1881141 and ABIN2841140) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (CBS 抗体 (N-Term))

Western blot analysis of CBS (arrow) using rabbit polyclonal CBS Antibody (N-term) (ABIN1881141 and ABIN2841140). (CBS 抗体 (N-Term))

CBS Antibody (N-term) (ABIN1881141 and ABIN2841140) flow cytometric analysis of Ramos cells (bottom histogram) compared to a negative control cell (top histogram). (CBS 抗体 (N-Term))

FACS

CBS Antibody (N-term) (ABIN1881141 and ABIN2841140) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. (CBS 抗体 (N-Term))

IHC (p)

5 images

(2 references)

产品编号 ABIN1881141

发货至: 中国

Datasheet as PDF

抗原 See all CBS 抗体

CBS (Cystathionine-beta-Synthase (CBS))
抗原表位
15

9

6

6

4

4

2

2

2

2

1

1

1

1

1

1
AA 104-133, N-Term
适用
54

40

12

4

2

2

2

2

1

1

1

1

1
人, 小鼠
宿主
65

9
兔
Compatible Secondaries
克隆类型
59

15
多克隆
标记
39

6

6

4

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CBS antibody is un-conjugated
应用范围
56

31

17

14

14

13

13

7

5

5

3

2

2

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This CBS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human CBS.

克隆位点

RB22961

亚型

Ig Fraction

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CBS 适用: 人 WB, ELISA, IHC (p), IP, RNAi 宿主: 小鼠 Monoclonal 3E1 unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 252-551) antibody
CBS 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-100) antibody
CBS 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6A9 unconjugated

anti-Cystathionine-beta-Synthase (CBS) (N-Term) antibody
CBS 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Saccharomyces cerevisiae, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-413) antibody
CBS 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) antibody
CBS 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) antibody
KO Validated CBS 适用: 人 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 301-330) antibody
CBS 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB21183 unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-551) antibody
CBS 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-551) antibody
CBS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Lee, Feliers, Mariappan, Sataranatarajan, Choudhury, Gorin, Kasinath: "Tadalafil Integrates Nitric Oxide-Hydrogen Sulfide Signaling to Inhibit High Glucose-induced Matrix Protein Synthesis in Podocytes." in: The Journal of biological chemistry, Vol. 290, Issue 19, pp. 12014-26, (2015) (PubMed).

Lee, Mariappan, Feliers, Cavaglieri, Sataranatarajan, Abboud, Choudhury, Kasinath: "Hydrogen sulfide inhibits high glucose-induced matrix protein synthesis by activating AMP-activated protein kinase in renal epithelial cells." in: The Journal of biological chemistry, Vol. 287, Issue 7, pp. 4451-61, (2012) (PubMed).
抗原

CBS (Cystathionine-beta-Synthase (CBS))

别名

CBS (CBS 产品)

别名

hip4 antibody, GB12529 antibody, CBS antibody, DDBDRAFT_0189727 antibody, DDBDRAFT_0191292 antibody, DDB_0189727 antibody, DDB_0191292 antibody, cbs antibody, AI047524 antibody, AI303044 antibody, HIP4 antibody, cb442 antibody, wu:fb37g05 antibody, wu:fm61c07 antibody, wu:fq06c06 antibody, zgc:113704 antibody, cystathionine-beta-synthase L homeolog antibody, cystathionine-beta-synthase antibody, cystathionine beta-synthase antibody, cystathionine beta-synthase CBS antibody, cystathionine beta synthase antibody, cystathionine-beta-synthase S homeolog antibody, cystathionine-beta-synthase b antibody, cbs.L antibody, cbs antibody, Cbs antibody, CBS antibody, CNA06170 antibody, Tb11.02.5400 antibody, cysB antibody, LOC100635325 antibody, cbs.S antibody, cbsb antibody

背景

CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria.

分子量

60587

NCBI登录号

NP_000062, NP_001171479, NP_001171480

UniProt

P35520