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- 抗原 See all CASR 抗体
- CASR (Calcium-Sensing Receptor (CASR))
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抗原表位
- AA 260-287
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CASR antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- B, Pig, Rat
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This CASR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-287 amino acids from the Central region of human CASR.
- 克隆位点
- RB41198
- 亚型
- IgG
- Top Product
- Discover our top product CASR Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels." in: Human molecular genetics, Vol. 19, Issue 21, pp. 4296-303, (2010) (PubMed).
: "High-density polymorphisms analysis of 23 candidate genes for association with bone mineral density." in: Bone, Vol. 47, Issue 5, pp. 975-81, (2010) (PubMed).
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Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels." in: Human molecular genetics, Vol. 19, Issue 21, pp. 4296-303, (2010) (PubMed).
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- 抗原
- CASR (Calcium-Sensing Receptor (CASR))
- 别名
- CASR (CASR 产品)
- 别名
- CAR antibody, EIG8 antibody, FHH antibody, FIH antibody, GPRC2A antibody, HHC antibody, HHC1 antibody, HYPOC1 antibody, NSHPT antibody, PCAR1 antibody, CaR antibody, Gprc2a antibody, gprc2a antibody, xV2R F-1 antibody, CASR antibody, calcium sensing receptor antibody, calcium-sensing receptor antibody, calcium-sensing receptor L homeolog antibody, CASR antibody, Casr antibody, casr.L antibody
- 背景
- The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq].
- 分子量
- 120675
- NCBI登录号
- NP_000379, NP_001171536
- UniProt
- P41180
- 途径
- Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
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