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BRMS1 抗体 (N-Term)

BRMS1 适用: 人 WB 宿主: 兔 Polyclonal RB40250 unconjugated
产品编号 ABIN1881120
发货至: 中国
  • 抗原 See all BRMS1 抗体
    BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
    抗原表位
    • 15
    • 7
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 48-77, N-Term
    适用
    • 53
    • 25
    • 24
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 51
    • 2
    克隆类型
    • 51
    • 2
    多克隆
    标记
    • 22
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BRMS1 antibody is un-conjugated
    应用范围
    • 46
    • 22
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    预测反应
    M, Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This BRMS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-77 amino acids from the N-terminal region of human BRMS1.
    克隆位点
    RB40250
    亚型
    Ig Fraction
    Top Product
    Discover our top product BRMS1 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Wu, McEwen, Harihar, Baker, DeWald, Zhou: "BRMS1 expression alters the ultrastructural, biomechanical and biochemical properties of MDA-MB-435 human breast carcinoma cells: an AFM and Raman microspectroscopy study." in: Cancer letters, Vol. 293, Issue 1, pp. 82-91, (2010) (PubMed).

    Vaidya, Sanchez, Kim, Welch: "Expression of the Breast Cancer Metastasis Suppressor 1 (BRMS1) maintains in vitro chemosensitivity of breast cancer cells." in: Cancer letters, Vol. 281, Issue 1, pp. 100-7, (2009) (PubMed).

    Frolova, Edmonds, Bodenstine, Seitz, Johnson, Feng, Welch, Frost: "A shift from nuclear to cytoplasmic breast cancer metastasis suppressor 1 expression is associated with highly proliferative estrogen receptor-negative breast cancers." in: Tumour biology, Vol. 30, Issue 3, pp. 148-59, (2009) (PubMed).

    Cicek, Fukuyama, Cicek, Sizemore, Welch, Sizemore, Casey: "BRMS1 contributes to the negative regulation of uPA gene expression through recruitment of HDAC1 to the NF-kappaB binding site of the uPA promoter." in: Clinical & experimental metastasis, Vol. 26, Issue 3, pp. 229-37, (2009) (PubMed).

  • 抗原
    BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
    别名
    BRMS1 (BRMS1 产品)
    别名
    MGC98869 antibody, BRMS1 antibody, BRMS1L antibody, AV003220 antibody, AW554636 antibody, si:zc188c22.3 antibody, si:zc194c5.2 antibody, wu:fb57b08 antibody, zgc:56414 antibody, breast cancer metastasis suppressor 1 antibody, breast cancer metastasis-suppressor 1 antibody, breast cancer metastasis suppressor 1 L homeolog antibody, BRMS1 antibody, Brms1 antibody, brms1.L antibody, brms1 antibody
    背景
    This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
    分子量
    28461
    NCBI登录号
    NP_056214
    UniProt
    Q9HCU9
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