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- 抗原 See all BRAF 抗体
- BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BRAF antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This BRAF antibody is generated from rabbits immunized with BRAF recombinant protein.
- 克隆位点
- RB22681
- 亚型
- Ig Fraction
- Top Product
- Discover our top product BRAF Primary Antibody
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- 应用备注
- WB: 1:1000. FC: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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BRAF drives synovial fibroblast transformation in rheumatoid arthritis." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34299-303, (2010) (PubMed).
: "Suppression of BRAF(V599E) in human melanoma abrogates transformation." in: Cancer research, Vol. 63, Issue 17, pp. 5198-202, (2003) (PubMed).
: "BRAF mutations in non-Hodgkin's lymphoma." in: British journal of cancer, Vol. 89, Issue 10, pp. 1958-60, (2003) (PubMed).
: "Mutations of the BRAF gene in human cancer. ..." in: Nature, Vol. 417, Issue 6892, pp. 949-54, (2002) (PubMed).
: "Missense mutations of the BRAF gene in human lung adenocarcinoma." in: Cancer research, Vol. 62, Issue 23, pp. 7001-3, (2002) (PubMed).
: "95-kilodalton B-Raf serine/threonine kinase: identification of the protein and its major autophosphorylation site." in: Molecular and cellular biology, Vol. 12, Issue 9, pp. 3733-42, (1992) (PubMed).
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BRAF drives synovial fibroblast transformation in rheumatoid arthritis." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34299-303, (2010) (PubMed).
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- 抗原
- BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))
- 别名
- BRAF (BRAF 产品)
- 别名
- B-RAF1 antibody, BRAF1 antibody, NS7 antibody, RAFB1 antibody, C-RMIL antibody, RMIL antibody, B-Raf antibody, braf1 antibody, rafb1 antibody, b-raf1 antibody, sierrabraf antibody, BRAF antibody, 9930012E13Rik antibody, AA120551 antibody, AA387315 antibody, AA473386 antibody, B-raf antibody, Braf-2 antibody, Braf2 antibody, C230098H17 antibody, C87398 antibody, D6Ertd631e antibody, braf antibody, fc48g01 antibody, wu:fc48g01 antibody, B-Raf proto-oncogene, serine/threonine kinase antibody, B-Raf proto-oncogene, serine/threonine kinase S homeolog antibody, Braf transforming gene antibody, si:dkey-222f8.3 antibody, BRAF antibody, Braf antibody, braf.S antibody, braf antibody, si:dkey-222f8.3 antibody
- 背景
- BRAF, a member of the RAF subfamily of Ser/Thr protein kinases, is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neurons. This cytoplasmic protein is expressed in brain and testis. Defects in BRAF are involved in a wide range of cancers including lung cancer and non-Hodgkin lymphoma (NHL). This protein contains 1 zinc-dependent phorbol-ester and DAG binding domain.
- 分子量
- 84437
- NCBI登录号
- NP_004324
- UniProt
- P15056
- 途径
- MAPK Pathway, RTK signaling, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy
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