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- 抗原 See all ASCL1 抗体
- ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
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抗原表位
- AA 63-90, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ASCL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This ASCL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-90 amino acids from the N-terminal region of human ASCL1.
- 克隆位点
- RB41522
- 亚型
- Ig Fraction
- Top Product
- Discover our top product ASCL1 Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Upregulation of SOX2, NOTCH1, and ID1 in supratentorial primitive neuroectodermal tumors: a distinct differentiation pattern from that of medulloblastomas." in: Journal of neurosurgery. Pediatrics, Vol. 5, Issue 6, pp. 608-14, (2010) (PubMed).
: "Efficient discovery of ASCL1 regulatory sequences through transgene pooling." in: Genomics, Vol. 95, Issue 6, pp. 363-9, (2010) (PubMed).
: "[Expression and clinicopathologic significance of human achaete-scute homolog 1 in pulmonary neuroendocrine tumors]." in: Zhongguo fei ai za zhi = Chinese journal of lung cancer, Vol. 13, Issue 4, pp. 317-21, (2010) (PubMed).
: "Examination of the MASH1 gene in patients with Parkinson's disease." in: Biochemical and biophysical research communications, Vol. 392, Issue 4, pp. 548-50, (2010) (PubMed).
: "ASCL1 regulates the expression of the CHRNA5/A3/B4 lung cancer susceptibility locus." in: Molecular cancer research : MCR, Vol. 8, Issue 2, pp. 194-203, (2010) (PubMed).
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Upregulation of SOX2, NOTCH1, and ID1 in supratentorial primitive neuroectodermal tumors: a distinct differentiation pattern from that of medulloblastomas." in: Journal of neurosurgery. Pediatrics, Vol. 5, Issue 6, pp. 608-14, (2010) (PubMed).
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- 抗原
- ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
- 别名
- ASCL1 (ASCL1 产品)
- 背景
- This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.
- 分子量
- 25454
- NCBI登录号
- NP_004307
- UniProt
- P50553
- 途径
- Dopaminergic Neurogenesis
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