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- 抗原 See all AKTIP 抗体
- AKTIP (AKT Interacting Protein (AKTIP))
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抗原表位
- AA 262-288, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AKTIP antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- C, Pr, M, Rat
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This AKTIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-288 amino acids from the C-terminal region of human AKTIP.
- 克隆位点
- RB38675
- 亚型
- Ig Fraction
- Top Product
- Discover our top product AKTIP Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival." in: Human molecular genetics, Vol. 18, Issue 10, pp. 1869-78, (2009) (PubMed).
: "An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex." in: Molecular biology of the cell, Vol. 19, Issue 12, pp. 5059-71, (2008) (PubMed).
: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, (2007) (PubMed).
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Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival." in: Human molecular genetics, Vol. 18, Issue 10, pp. 1869-78, (2009) (PubMed).
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- 抗原
- AKTIP (AKT Interacting Protein (AKTIP))
- 别名
- AKTIP (AKTIP 产品)
- 别名
- FT1 antibody, FTS antibody, cb798 antibody, fts antibody, zgc:77699 antibody, fts-A antibody, aktip antibody, fts-B antibody, MGC133931 antibody, AL023020 antibody, Fif antibody, Ft antibody, Ft1 antibody, Fts antibody, AKT interacting protein antibody, akt interacting protein antibody, AKT interacting protein L homeolog antibody, AKT interacting protein S homeolog antibody, thymoma viral proto-oncogene 1 interacting protein antibody, AKTIP antibody, aktip antibody, aktip.L antibody, aktip.S antibody, Aktip antibody
- 背景
- The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.
- 分子量
- 33128
- NCBI登录号
- NP_001012398, NP_071921
- UniProt
- Q9H8T0
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