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PGRMC1 抗体 (C-Term)

Verified PGRMC1 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN185610
发货至: 中国
  • 抗原 See all PGRMC1 抗体
    PGRMC1 (Progesterone Receptor Membrane Component 1 (PGRMC1))
    抗原表位
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 22
    • 15
    • 14
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 20
    • 2
    山羊
    克隆类型
    • 20
    • 2
    多克隆
    标记
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PGRMC1 antibody is un-conjugated
    应用范围
    • 14
    • 10
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    原理
    PGRMC1 / MPR
    序列
    EPKDESARKN D
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    质量等级
    Verified
    免疫原
    Peptide with sequence C-EPKDESARKND, from the C Terminus of the protein sequence according to NP_006658.1.
    亚型
    IgG
  • 应用备注

    Immunohistochemistry: Paraffin embedded Human Testis. Recommended concentration: 5 μg/mL.

    Western Blot: Approx 24 kDa band observed in Human Kidney, Liver and Testis lysates, and approx 25 kDa in Mouse Testis lysates (calculated MW of 21.7 kDa according to Human NP_006658.1 and Mouse NP_058063.2). These molecular weights are routinely observed b

    Peptide ELISA: antibody detection limit dilution 1:4000.

    说明

    Immunofluorescence: This antibody has been successfully used in IF on Human: Izzo, N. J et al. (2014) PMID: 25390692.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Minimize freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Izzo, Xu, Zeng, Kirk, Mozzoni, Silky, Rehak, Yurko, Look, Rishton, Safferstein, Cruchaga, Goate, Cahill, Arancio, Mach, Craven, Head, LeVine, Spires-Jones, Catalano: "Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity." in: PLoS ONE, Vol. 9, Issue 11, pp. e111899, (2015) (PubMed).

  • 抗原
    PGRMC1 (Progesterone Receptor Membrane Component 1 (PGRMC1))
    别名
    PGRMC1 (PGRMC1 产品)
    别名
    MGC89150 antibody, wu:fa94d03 antibody, zgc:103577 antibody, DKFZp469D0815 antibody, HPR6.6 antibody, MPR antibody, AA415812 antibody, PPMR antibody, Vema antibody, 25-Dx antibody, 25Dx antibody, VEMA antibody, progesterone receptor membrane component 1 antibody, pgrmc1 antibody, PGRMC1 antibody, Pgrmc1 antibody
    背景
    PGRMC1, MPR, progesterone receptor membrane component 1 , HGNC:16090, HPR6.6, progesterone binding protein
    基因ID
    10857, 53328
    NCBI登录号
    NP_006658
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