ADRB1 抗体 (Internal Region)
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- 抗原 See all ADRB1 抗体
- ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This ADRB1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- ADRB1
- 序列
- ESDEARRCYN DPK
- 交叉反应
- 犬, 人, 小鼠, 大鼠
- 纯化方法
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- 质量等级
- Verified
- 免疫原
- Peptide with sequence ESDEARRCYNDPK, from the internal region of the protein sequence according to NP_000675.1.
- 亚型
- IgG
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- 应用备注
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Immunohistochemistry: Paraffin embedded Human Heart. Recommended concentration: 6 μg/mL.
Western Blot: This antibody is not recommended for use in Western blotting.
Peptide ELISA: antibody detection limit dilution 1:2000.
- 说明
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Immunofluorescence: Strong expression of the protein seen in the plama membrane and cytoplasm of HeLa cells. Recommended concentration: 10μg/ml.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Minimize freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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Difference between beta1-adrenoceptor autoantibodies of human and animal origin-Limitations detecting beta1-adrenoceptor autoantibodies using peptide based ELISA technology." in: PLoS ONE, Vol. 13, Issue 2, pp. e0192615, (2018) (PubMed).
: "Functional autoantibodies in patients with different forms of dementia." in: PLoS ONE, Vol. 13, Issue 3, pp. e0192778, (2018) (PubMed).
: "Performance and in-house validation of a bioassay for the determination of beta1-autoantibodies found in patients with cardiomyopathy." in: Heliyon, Vol. 3, Issue 7, pp. e00362, (2017) (PubMed).
: "The first aptamer-apheresis column specifically for clearing blood of ?1-receptor autoantibodies." in: Circulation journal : official journal of the Japanese Circulation Society, Vol. 76, Issue 10, pp. 2449-55, (2012) (PubMed).
: "Aptamer neutralization of beta1-adrenoceptor autoantibodies isolated from patients with cardiomyopathies." in: Circulation research, Vol. 109, Issue 9, pp. 986-92, (2011) (PubMed).
: "Distinct patterns of autoantibodies against G-protein-coupled receptors in Chagas' cardiomyopathy and megacolon. Their potential impact for early risk assessment in asymptomatic Chagas' patients." in: Journal of the American College of Cardiology, Vol. 55, Issue 5, pp. 463-8, (2010) (PubMed).
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Difference between beta1-adrenoceptor autoantibodies of human and animal origin-Limitations detecting beta1-adrenoceptor autoantibodies using peptide based ELISA technology." in: PLoS ONE, Vol. 13, Issue 2, pp. e0192615, (2018) (PubMed).
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- 抗原
- ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))
- 别名
- ADRB1 (ADRB1 产品)
- 别名
- ADRB1R antibody, B1AR antibody, BETA1AR antibody, RHR antibody, RATB1AR antibody, X-Beta1AR antibody, BAR1 antibody, zgc:194728 antibody, zgc:194731 antibody, ADRB1 antibody, Adrb-1 antibody, beta-AR antibody, adrenoceptor beta 1 antibody, adrenoceptor beta 1 L homeolog antibody, adrenergic, beta-1-, receptor antibody, adrenergic receptor, beta 1 antibody, ADRB1 antibody, Adrb1 antibody, adrb1.L antibody, adrb1 antibody
- 背景
- ADRB1, adrenergic, beta-1-, receptor, ADRB1R, B1AR, BETA1AR, RHR, beta-1-adrenergic receptor
- 分子量
- 51.2kDa
- 基因ID
- 153
- NCBI登录号
- NP_000675
- 途径
- cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Brown Fat Cell Differentiation
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