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KPNA3 抗体 (C-Term)

Verified KPNA3 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN185159
发货至: 中国
  • 抗原 See all KPNA3 抗体
    KPNA3 (Karyopherin alpha 3 (Importin alpha 4) (KPNA3))
    抗原表位
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 34
    • 28
    • 25
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 30
    • 2
    • 1
    • 1
    山羊
    克隆类型
    • 32
    • 2
    多克隆
    标记
    • 18
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KPNA3 antibody is un-conjugated
    应用范围
    • 31
    • 14
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
    原理
    KPNA3 / IPOA4
    序列
    DPTANLQTKE FNF
    交叉反应
    Cow, 犬, 人, 小鼠, 大鼠
    纯化方法
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    质量等级
    Verified
    免疫原
    Peptide with sequence C-DPTANLQTKEFNF, from the C Terminus of the protein sequence according to NP_002258.2.
    亚型
    IgG
    Top Product
    Discover our top product KPNA3 Primary Antibody
  • 应用备注

    Immunohistochemistry: Paraffin embedded Human Testis. Recommended concentration: 6 μg/mL.

    Western Blot: Approx. 60 kDa band observed in lysates of cell lines CaCo-2, HEK293 and MCF7 (calculated MW of 57.8 kDa according to NP_002258.2). Recommended concentration: 0.01-0.03 μg/mL. Primary incubation 1 hour at room temperature.

    Peptide ELISA: antibody detection limit dilution 1:128000.

    说明

    Immunofluorescence: Strong expression of the protein seen in the cytoplasm and nuclei of A431 cells. Recommended concentration: 10μg/ml.

    Flow Cytometry: Flow cytometric analysis of A431 cells. Recommended concentration

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Minimize freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Jovičić, Mertens, Boeynaems, Bogaert, Chai, Yamada, Paul, Sun, Herdy, Bieri, Kramer, Gage, Van Den Bosch, Robberecht, Gitler: "Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS." in: Nature neuroscience, Vol. 18, Issue 9, pp. 1226-9, (2015) (PubMed).

    Ohara, Hata, Yasuhara, Mehmood, Yoneda, Nakagawa, Yamashita: "Axotomy induces axonogenesis in hippocampal neurons by a mechanism dependent on importin ?." in: Biochemical and biophysical research communications, Vol. 405, Issue 4, pp. 697-702, (2011) (PubMed).

    Huenniger, Krämer, Soom, Chang, Köhler, Depping, Kehlenbach, Kaether: "Notch1 signaling is mediated by importins alpha 3, 4, and 7." in: Cellular and molecular life sciences : CMLS, Vol. 67, Issue 18, pp. 3187-96, (2010) (PubMed).

  • 抗原
    KPNA3 (Karyopherin alpha 3 (Importin alpha 4) (KPNA3))
    别名
    KPNA3 (KPNA3 产品)
    别名
    IPOA4 antibody, si:dz79f24.2 antibody, importin antibody, SRP1 antibody, SRP1gamma antibody, SRP4 antibody, hSRP1 antibody, ipoa4 antibody, srp1 antibody, srp1gamma antibody, srp4 antibody, karyopherin (importin) alpha 3 antibody, karyopherin alpha 3 (importin alpha 4) antibody, karyopherin subunit alpha 3 antibody, karyopherin alpha 3 (importin alpha 4) L homeolog antibody, Kpna3 antibody, kpna3 antibody, KPNA3 antibody, kpna3.L antibody
    背景
    KPNA3, IPOA4, karyopherin alpha 3 (importin alpha 4), RP11-432M24.3, SRP1gamma, SRP4, hSRP1, importin alpha 4, importin alpha 4, importin-alpha-Q2, karyopherin alpha 3, SRP1, importin alpha-3
    基因ID
    3839, 16648
    NCBI登录号
    NP_002258
    途径
    Protein targeting to Nucleus
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