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ROCK1 抗体
ROCK1
适用: 人
WB, ELISA
宿主: 小鼠
Monoclonal
unconjugated
ROCK1抗体详情
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抗原
See all ROCK1 抗体
ROCK1
(rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
适用
All reactivities for ROCK1 抗体
人
宿主
All hosts for ROCK1 抗体
小鼠
克隆类型
All clonalities for ROCK1 抗体
单克隆
标记
All conjugates for ROCK1 抗体
This ROCK1 antibody is un-conjugated
应用范围
All applications for ROCK1 抗体
Western Blotting (WB), ELISA
纯化方法
Purified antibody
免疫原
Purified recombinant fragment of human ROCK1 expressed in E. Coli.
亚型
IgG1
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Discover our top product ROCK1 Primary Antibody
Alternatives
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anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (pSer456), (pThr455) antibody
ROCK1
适用: 人, 小鼠, 大鼠
WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1.0 mg/mL
缓冲液
PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
ROCK1目标详情
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抗原
ROCK1
(rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
别名
ROCK1 (ROCK1 产品 )
别名
LOC100229794 antibody, CG9774 antibody, DROK antibody, DRhk antibody, DRok antibody, Dmel\\CG9774 antibody, Drok antibody, ROCK antibody, ROCK-1 antibody, ROCK1 antibody, ROK antibody, ROKalpha/beta antibody, Rhk antibody, RhoK antibody, Rock antibody, Rok antibody, dROK antibody, dRok antibody, drok antibody, 1110055K06Rik antibody, Rock-I antibody, P160Rock antibody, ROCK-I antibody, P160ROCK antibody, p160ROCK antibody, Rho associated coiled-coil containing protein kinase 1 antibody, Rho kinase antibody, Rho-associated coiled-coil containing protein kinase 1 antibody, Rho-associated, coiled-coil containing protein kinase 1 antibody, ROCK1 antibody, Rok antibody, Rock1 antibody, rock1 antibody
背景
This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity.
分子量
158 kDa
基因ID
6093
UniProt
Q13464
途径
Microtubule Dynamics , WNT signaling , M Phase , Maintenance of Protein Location , Signaling Events mediated by VEGFR1 and VEGFR2 , Thromboxane A2 Receptor Signaling
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