KREV-1 antibody, KREV1 antibody, RAP1 antibody, SMGP21 antibody, AI848598 antibody, G-22K antibody, Krev-1 antibody, Rap1 antibody, RAP-1A antibody, rap 1A antibody, wu:fc66g06 antibody, zgc:86676 antibody, krev-1 antibody, krev1 antibody, rap1 antibody, RAP1A, member of RAS oncogene family antibody, RAS-related protein 1a antibody, RAP1A, member of RAS oncogene family a antibody, RAP1A, member of RAS oncogene family L homeolog antibody, RAP1A antibody, Rap1a antibody, rap1aa antibody, rap1a.L antibody
背景
The product of this gene belongs to the family of RAS-related proteins.These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common.The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins.The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner.Two transcript variants encoding the same protein have been identified for this gene.