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INCENP 抗体 (AA 369-583)

INCENP 适用: 人 WB, FACS, ELISA, IHC, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN1844019
发货至: 中国
  • 抗原 See all INCENP 抗体
    INCENP (Inner Centromere Protein Antigens 135/155kDa (INCENP))
    抗原表位
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 369-583
    适用
    • 26
    • 10
    • 10
    • 1
    • 1
    • 1
    宿主
    • 15
    • 11
    小鼠
    克隆类型
    • 15
    • 11
    单克隆
    标记
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This INCENP antibody is un-conjugated
    应用范围
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Immunofluorescence (fixed cells) (IF/ICC)
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human INCENP (AA: 369-583) expressed in E. Coli.
    亚型
    IgG1
    Top Product
    Discover our top product INCENP Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
  • 抗原
    INCENP (Inner Centromere Protein Antigens 135/155kDa (INCENP))
    别名
    INCENP (INCENP 产品)
    别名
    INCENP antibody, LOC572121 antibody, 2700067E22Rik antibody, AU019509 antibody, C130081E20 antibody, C77457 antibody, XL-INCENP antibody, incenp antibody, incenp-a antibody, incenp-b antibody, xINC antibody, xIncenp antibody, xl-incenp antibody, inner centromere protein antibody, inner centromere protein S homeolog antibody, inner centromere protein L homeolog antibody, INCENP antibody, Incenp antibody, incenp.S antibody, incenp antibody, incenp.L antibody
    背景
    In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger,' or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA (centromere protein A, MIM 117139), CENPB (MIM 117140), CENPC1 (MIM 117141), and CENPD (MIM 117142). The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle (Earnshaw and Mackay, 1994 [PubMed 8088460]). These include CENPE (MIM 117143), MCAK (MIM 604538), KID (MIM 603213), cytoplasmic dynein (e.g., MIM 600112), CliPs (e.g., MIM 179838), and CENPF/mitosin (MIM 600236). The inner centromere proteins (INCENPs) (Earnshaw and Cooke, 1991 [PubMed 1860899]), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis.
    分子量
    105.4 kDa
    基因ID
    3619
    UniProt
    Q9NQS7
    途径
    Cell Division Cycle
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