CXCR4 抗体 (AA 17-43)
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- 抗原 See all CXCR4 抗体
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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抗原表位
- AA 17-43
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适用
- 人
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This CXCR4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- Recognizes an epitope within the N-terminal (NT) region of human CD184, otherwise known as CXCR4 (C-X-C chemokine receptor type 4), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, ubiquitously expressed in blood and tissue cells, which acts as a specific receptor for the chemokine SDF-1 (Stromal cell-derived factor 1). Interaction of CD184 with SDF-1 mediates the chemotaxis of progenitor and mature blood cells, and is critical for B- lymphopoiesis and myelopoiesis. CD184 is a major co-receptor for infection by T-cell tropic strains of HIV1, and also a primary receptor for some HIV2 isolates. Thisis reported as being suitable for use in immunofluorescence studies.
- 纯化方法
- Affinity purified
- 免疫原
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Synthetic peptide TEEMGSGDYDSMKEPCFREENANFNKC corresponding to amino acids 17-43 within the N-terminal region of human CD184. Percent identity by BLAST analysis: Human, Chimpanzee (100%), Gorilla, Orangutan, Gibbon, Monkey (96%), Baboon, Tamarin, Dog (88%), Galago, Marmoset, Sheep, Elephant, Panda, Bovine, Cat, Rabbit (85%), Horse, Pig (81%).
Type of Immunogen: Synthetic peptide - 亚型
- IgG
- Top Product
- Discover our top product CXCR4 Primary Antibody
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- 应用备注
- Approved: ELISA (1:25000), IHC, IHC-P (1:150), WB (1:250)
- 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, 1 % BSA, 0.1 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- 抗原
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
- 别名
- CXCR4 (CXCR4 产品)
- 背景
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Name/Gene ID: CXCR4
Subfamily: Chemokine
Family: GPCR
Synonyms: CXCR4, CD184, CD184 antigen, Cmkar4, Cxc chemokine receptor 4, CXCR-4, CXC-R4, D2S201E, FB22, Fusin, HM89, LCR1, NPY3R, NPYRL, NPYY3R, Npyy3, HSY3RR, SDF-1 receptor, WHIM, C-x-c chemokine receptor 4, LESTR, Neuropeptide Y receptor Y3, NPYR - 基因ID
- 7852
- 途径
- Regulation of Cell Size, CXCR4-mediated Signaling Events
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