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CXCR4 抗体 (AA 17-43)

CXCR4 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN1819412
发货至: 中国
  • 抗原 See all CXCR4 抗体
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    抗原表位
    • 18
    • 15
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    • 7
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    AA 17-43
    适用
    • 131
    • 84
    • 66
    • 21
    • 11
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    • 4
    • 4
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    宿主
    • 113
    • 22
    • 9
    • 5
    • 1
    山羊
    克隆类型
    • 120
    • 30
    多克隆
    标记
    • 96
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    This CXCR4 antibody is un-conjugated
    应用范围
    • 110
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Recognizes an epitope within the N-terminal (NT) region of human CD184, otherwise known as CXCR4 (C-X-C chemokine receptor type 4), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, ubiquitously expressed in blood and tissue cells, which acts as a specific receptor for the chemokine SDF-1 (Stromal cell-derived factor 1). Interaction of CD184 with SDF-1 mediates the chemotaxis of progenitor and mature blood cells, and is critical for B- lymphopoiesis and myelopoiesis. CD184 is a major co-receptor for infection by T-cell tropic strains of HIV1, and also a primary receptor for some HIV2 isolates. Thisis reported as being suitable for use in immunofluorescence studies.
    纯化方法
    Affinity purified
    免疫原
    Synthetic peptide TEEMGSGDYDSMKEPCFREENANFNKC corresponding to amino acids 17-43 within the N-terminal region of human CD184. Percent identity by BLAST analysis: Human, Chimpanzee (100%), Gorilla, Orangutan, Gibbon, Monkey (96%), Baboon, Tamarin, Dog (88%), Galago, Marmoset, Sheep, Elephant, Panda, Bovine, Cat, Rabbit (85%), Horse, Pig (81%).

    Type of Immunogen: Synthetic peptide
    亚型
    IgG
    Top Product
    Discover our top product CXCR4 Primary Antibody
  • 应用备注
    Approved: ELISA (1:25000), IHC, IHC-P (1:150), WB (1:250)
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS, 1 % BSA, 0.1 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    4°C or -20°C, Avoid freeze-thaw cycles.
  • 抗原
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    别名
    CXCR4 (CXCR4 产品)
    背景
    Name/Gene ID: CXCR4
    Subfamily: Chemokine
    Family: GPCR

    Synonyms: CXCR4, CD184, CD184 antigen, Cmkar4, Cxc chemokine receptor 4, CXCR-4, CXC-R4, D2S201E, FB22, Fusin, HM89, LCR1, NPY3R, NPYRL, NPYY3R, Npyy3, HSY3RR, SDF-1 receptor, WHIM, C-x-c chemokine receptor 4, LESTR, Neuropeptide Y receptor Y3, NPYR
    基因ID
    7852
    途径
    Regulation of Cell Size, CXCR4-mediated Signaling Events
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