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SIGLEC10 抗体 (FITC)

SIGLEC10 适用: 人 FACS 宿主: 小鼠 Monoclonal 5G6 FITC
产品编号 ABIN1819171
发货至: 中国
  • 抗原 See all SIGLEC10 抗体
    SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))
    适用
    • 41
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    宿主
    • 34
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    小鼠
    克隆类型
    • 35
    • 7
    单克隆
    标记
    • 16
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    • 6
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    This SIGLEC10 antibody is conjugated to FITC
    应用范围
    • 28
    • 25
    • 7
    • 5
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    Flow Cytometry (FACS)
    特异性
    Clone 5G6 specifically recognizes human Siglec-10 (Sialic acid-binding Ig-like lectin 10), a putative adhesion molecule and member of the Ig superfamily, expressed by monocytes, B cells, eosinophils, and at a higher level by a subpopulation of CD16+CD56- natural killer (NK) cells. Structurally, Siglec-10 is most similar to the CD33-related group of Siglecs, and preferentially binds to glycoconjugates containing alpha-2,3- or alpha-2,6-linked sialic acid. Studies have shown that Siglec-10 acts as a substrate for VAP-1 (Vascular adhesion protein-1), a glycoprotein expressed on endothelium during inflammation, which is involved in primary amine oxidation and leucocyte trafficking, see for details. This interaction between Siglec-10 and VAP-1, implicates Siglec-10 in endothelial lymphocyte adhesion and in the modulation of the inflammatory microenvironment. Studies have shown that clone 5G6 does not cross-react with Siglecs 3, 5, 7, 8 and 9, see for details.
    纯化方法
    Protein G purified
    免疫原
    Recombinant human Siglec-10, fused with the Fc region of human IgG.

    Type of Immunogen: Recombinant protein
    克隆位点
    5G6
    亚型
    IgG1
    Top Product
    Discover our top product SIGLEC10 Primary Antibody
  • 应用备注
    Approved: Flo

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS, 0.09 % sodium azide, 1 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    4°C or -20°C, Avoid freeze-thaw cycles.
  • 抗原
    SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))
    别名
    SIGLEC10 / SIGLEC-10 (SIGLEC10 产品)
    别名
    PRO940 antibody, SIGLEC-10 antibody, SLG2 antibody, Siglecg antibody, SIGLEC10 antibody, slg2 antibody, pro940 antibody, siglec-10 antibody, sialic acid binding Ig like lectin 10 antibody, sialic acid binding Ig-like lectin 10 antibody, sialic acid-binding Ig-like lectin 10 antibody, SIGLEC10 antibody, Siglec10 antibody, LOC484343 antibody, LOC100066644 antibody, siglec10 antibody, LOC100513863 antibody, LOC100340374 antibody
    背景
    Name/Gene ID: SIGLEC10

    Synonyms: SIGLEC10, SIGLEC-10, Siglec-like gene 2, Siglec-like protein 2, PRO940, SLG2
    基因ID
    89790
    UniProt
    Q96LC7
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