CD300a 抗体 (FITC)
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- 抗原 See all CD300a (CD300A) 抗体
- CD300a (CD300A)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD300a antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 特异性
- Recognizes human CD300a, otherwise known as IRp60 (inhibitory receptor protein 60), a 60kD transmembrane glycoprotein expressed by natural killer cells (NK), T and B cell subsets, monocytes, neutrophils, macrophages, granulocytes, dendritic cells (DC) and mast cells. Studies have shown that the cross-linking of CD300a on NK results in a down-regulation of their cytolytic activity, whilst cross-linking of CD300a on mast cells, inhibits IgE-induced degranulation and SCF-mediated survival. Furthermore, cross-linking of CD300a on the surface of eosinophils has been shown to significantly inhibit their survival, chemotaxis and activation in response to certain inflammatory cytokines, whilst eosinophil-derived MBP (major basic protein) and EDN (neurotoxin), can down-regulate CD300a expression on mast cells in vitro.
- 纯化方法
- Protein G purified
- 免疫原
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Polyclonal population of NK cells.
Type of Immunogen: Cells - 克隆位点
- P192
- 亚型
- IgG2a
- Top Product
- Discover our top product CD300A Primary Antibody
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- 应用备注
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Approved: Flo
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, 1 % BSA, 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- 抗原
- CD300a (CD300A)
- 别名
- CD300A (CD300A 产品)
- 别名
- CD300L-B1 antibody, CD300A antibody, clm8 antibody, B230315M08Rik antibody, Clm8 antibody, LMIR1 antibody, MAIR-I antibody, MAIR-Ia antibody, MMAC8 antibody, Pigr4 antibody, mcpir1 antibody, CLM-8 antibody, CMRF-35-H9 antibody, CMRF-35H antibody, CMRF35-H antibody, CMRF35-H9 antibody, CMRF35H antibody, CMRF35H9 antibody, IGSF12 antibody, IRC1 antibody, IRC1/IRC2 antibody, IRC2 antibody, IRp60 antibody, CD300 molecule like family member g antibody, CD300a molecule antibody, CMRF35-like molecule 8 antibody, CD300A molecule antibody, Cd300a molecule antibody, CD300LG antibody, CD300A antibody, LOC483289 antibody, clm8 antibody, Cd300a antibody
- 背景
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Name/Gene ID: CD300A
Synonyms: CD300A, CD300a antigen, CD300a molecule, CMRF35-like molecule 8, CMRF35-H, CMRF35-H9, CLM-8, CMRF35H9, IGSF12, Inhibitory receptor protein 60, IRC2, IRC1, NK inhibitory receptor, CMRF-35-H9, CMRF-35H, CMRF35H, IRC1a, IRp60, Leukocyte membrane antigen - 基因ID
- 11314
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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