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CD19 抗体 (APC)

CD19 适用: 人 FACS 宿主: 小鼠 Monoclonal LT19 APC
产品编号 ABIN181826
发货至: 中国
  • 抗原 See all CD19 抗体
    CD19 (CD19 Molecule (CD19))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD19 antibody is conjugated to APC
    应用范围
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    Flow Cytometry (FACS)
    特异性
    This antibody recognizes the CD19 cell surface antigen. It labels all B lymphocytes in peripheral blood and spleen but is negative on granulocytes, monocytes, platelets, T lymphocytes and erythrocytes. This antibody is useful for enumerating normal B lymphocytes and typing B cell malignancies by Flow cytometry and Immunofluorescence. The antibody reacts with most B cell malignancies including chronic leukaemia and most lymphomas, but not multiple myeloma.
    克隆位点
    LT19
    亚型
    IgG1
    Top Product
    Discover our top product CD19 Primary Antibody
  • 应用备注
    Flow Cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with 1 mL distilled water.
    缓冲液
    PBS, pH 7.4, containing 1 % BSA as stabilizer and 0.09 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Prior to and following reconstitution store the antibody at 2-8 °C for one month. Prior to reconstitution store at -20 °C for one year or following reconstitution at -20 °C for 6 month.
    有效期
    12 months
  • 抗原
    CD19 (CD19 Molecule (CD19))
    别名
    CD19 (CD19 产品)
    背景
    CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 Molecule is expressed on 100 % of the peripheral B cells as defined by expression of kappa or lamda light chains. It is expressed on approximately 10 % of normal human peripheral blood cells and approximately 60 % of splenic lymphocytes. It is not expressed on granulocytes, monocytes or T cells as defined by CD3 expression. CD19 defines a pan B antigen which is expressed from the earliest stages of B progenitor development, but is lost on terminal differentiation to plasma cells. It may also be present on some early myeloid progenitors, particularly those of the monoblastic type. The CD19 antigen is expressed on approximately 12 % of peripheral blood lymphocytes. It appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen.Synonyms: B-cell marker, B-lymphocyte surface antigen B4, Differentiation antigen CD19, Leu-12
    基因ID
    930
    NCBI登录号
    NP_001171569
    UniProt
    P15391
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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