Complement C4A/C4B 抗体
适用: 人
EIA, IHC (fro), FACS
宿主: 小鼠
Monoclonal
057-51-5-1-6
unconjugated
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- 抗原
- Complement C4A/C4B
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
- 特异性
- This antibody recognises a neoantigen on the secreted protein complement component 4d (C4d).
- 产品特性
- Synonyms: Complement component 4, CPAMD2, CPAMD3, Acidic complement C4, Basic complementC4
- 纯化方法
- Affinity chromatography on Protein A
- 免疫原
- Purified human C4d. Genename: C4d
- 克隆位点
- 057-51-5-1-6
- 亚型
- IgG1
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anti-Complement C4A/C4B (Internal Region) antibody
适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement C4A/C4B (Internal Region) antibody适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Flow Cytometry. Immunohistochemistry on frozen sections. Recommended Positive Control: Kidney from post streptoccal glomerulonephritis patients.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0mg/mL
- 缓冲液
- Borate buffered saline pH 8.2 - 8.4 containing 0.02 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- Complement C4A/C4B
- 背景
- The complement 1 complex cleaves complement 4 (C4) to form C4b and C4a. C4b levels are strictly regulated. Single site cleavage of the C4bs alpha chain by Factor I forms iC4b and blocks C3 convertase, inhibiting opsonisation and activation of the classical pathway. This requires C4 binding protein or CR1 as a cofactor. iC4b is further degraded into C4d and C4c. The short half life of C4d means that it is present in serum at high enough concentrations to make it a useful marker for classical complement activation. C4 has been linked to susceptibility to systemic lupus erythematosous.Synonyms: Acidic complement C4, Basic complement C4, CPAMD2, CPAMD3, Complement component 4
- 基因ID
- 720
- UniProt
- P0C0L4
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