EPH Receptor A2 抗体
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- 抗原 See all EPH Receptor A2 (EPHA2) 抗体
- EPH Receptor A2 (EPHA2)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This EPH Receptor A2 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Cell-ELISA (cELISA)
- 特异性
- Anti-human EphA2
- 纯化方法
- Protein G
- 免疫原
- genetic immunisation with cDNA encoding human EphA2
- 克隆位点
- Kalpha-5H5
- 亚型
- IgG1
- Top Product
- Discover our top product EPHA2 Primary Antibody
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- 应用备注
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Flow cytometry: 1.2 µg/10^6 cells
Immunofluorescence: 1 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - 说明
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Synonyms: Eph receptor tyrosine kinase A2
- 限制
- 仅限研究用
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- 浓度
- 2 mg/mL
- 缓冲液
- PBS, pH 7.2
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C
- 储存方法
- short term: 2 °C - 8 °C, long term: -20 °C
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- 抗原
- EPH Receptor A2 (EPHA2)
- 别名
- EPHA2 (EPHA2 产品)
- 别名
- ARCC2 antibody, CTPA antibody, CTPP1 antibody, CTRCT6 antibody, ECK antibody, epha2 antibody, MGC89505 antibody, AW545284 antibody, Eck antibody, Myk2 antibody, Sek-2 antibody, Sek2 antibody, id:ibd5152 antibody, rtk6 antibody, G42 antibody, XE10 antibody, epha2-A antibody, EPH receptor A2 antibody, Eph receptor A2 antibody, epoxide hydrolase antibody, eph receptor A2 a antibody, EPH receptor A2 L homeolog antibody, EPHA2 antibody, Epha2 antibody, epha2 antibody, ephA2 antibody, epha2a antibody, epha2.L antibody
- 背景
- EphA2 (Ephrin receptor tyrosine kinase A2) belongs to the Ephrin tyrosine receptor familiy, the largest receptor tyrosine kinase family of transmembrane proteins. It encodes a 130 kDA transmembrane protein which is primarily found in adult human epithelial cells. Eph receptors and their ephrin ligands are important mediators of cell-cell communication and play roles in embryonic patterning, neuronal targeting, and vascular development during normal embryogenesis. The Eph family of receptor tyrosine kinases is frequently overexpressed in a wide variety of cancers and tumor cell lines. In particular, EphA2 is overexpressed in prostate, lung and colon cancers and 40% of breast cancers and it represent an attractive potential target for drug design.
- UniProt
- P29317
- 途径
- RTK signaling
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