CCR4 抗体
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- 抗原 See all CCR4 抗体
- CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CCR4 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Cell-ELISA (cELISA)
- 特异性
- Anti-human CCR4
- 纯化方法
- Protein G
- 免疫原
- immunisation with human CCR4 peptide
- 克隆位点
- KH-4F5
- 亚型
- IgG2a
- Top Product
- Discover our top product CCR4 Primary Antibody
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- 应用备注
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Flow cytometry: 1.2 µg/10^6 cells
Immunofluorescence: 1 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - 说明
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Synonyms: CC chemokine receptor 4
- 限制
- 仅限研究用
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- 浓度
- 2 mg/mL
- 缓冲液
- PBS, pH 7.2
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C
- 储存方法
- short term: 2 °C - 8 °C, long term: -20 °C
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- 抗原
- CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
- 别名
- CCR4 (CCR4 产品)
- 别名
- CC-CKR-4 antibody, CD194 antibody, CKR4 antibody, CMKBR4 antibody, ChemR13 antibody, HGCN:14099 antibody, K5-5 antibody, Ccr4 antibody, C-C CKR-4 antibody, CHEMR1 antibody, Cmkbr4 antibody, LESTR antibody, Sdf1r antibody, C-C motif chemokine receptor 4 antibody, chemokine (C-C motif) receptor 4 antibody, CCR4 antibody, Ccr4 antibody
- 背景
- CCR4 (CC chemokine receptor 4) molecule belongs to the rhodopsin family of G-protein-coupled receptors. Chemokine receptors are membrane bound molecules composed of 7-transmembrane domains and coupled to G-proteins. CCR4 binds the chemokines CCL17 (TARC) and CCL22 (MDC) and is highly expressed in most single-positive CD4(+) thymocytes especially in TH2- and regulatory T-cells. It plays a central role in T cell migration to the thymus, T cell maturation and education. CCR4 is often up-regulated in inflammation and cause conformational changes that trigger intracellular signaling pathways.
- UniProt
- P51679
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