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TNC 抗体

TNC 适用: 大鼠, 小鼠 WB, IHC, ICC 宿主: 大鼠 Monoclonal 578 unconjugated
产品编号 ABIN1742432
发货至: 中国
  • 抗原 See all TNC 抗体
    TNC (Tenascin C (TNC))
    适用
    • 85
    • 43
    • 42
    • 15
    • 2
    • 2
    • 1
    • 1
    大鼠, 小鼠
    宿主
    • 74
    • 32
    • 2
    • 1
    • 1
    大鼠
    克隆类型
    • 69
    • 41
    单克隆
    标记
    • 46
    • 10
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    • 3
    • 2
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    • 2
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    • 1
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    This TNC antibody is un-conjugated
    应用范围
    • 72
    • 26
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    • 25
    • 24
    • 16
    • 13
    • 11
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    特异性
    Specific for tenascin-C splice variants carrying the FNIII D domain.
    纯化方法
    hybridoma supernatant
    免疫原
    Glycopeptidase F-treated tenascin from mouse brain. Epitope FNIII D domain
    克隆位点
    578
    亚型
    IgG
    Top Product
    Discover our top product TNC Primary Antibody
  • 应用备注
    1:10.000 recommended dilution
    说明

    Tenascin-C variants detected by this antibody are downregulated during development and hardly detectable in adult animals

    限制
    仅限研究用
  • 状态
    Liquid
    溶解方式
    For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
    缓冲液
    PBS
    注意事项
    When hybridoma supernatant is reconstituted, we usually add small amounts of azide or thimerosal to prevent microbial growth. Ascites should be stored frozen (-20 °C). Monoclonals usually do not suffer from repetitive freeze-thawing but you may aliquot them into small samples to avoid too many freeze-thaw cycles.
    Prolonged storage at 4 °C is not recommended! Unlike serum, ascites may contain proteases that will ultimately degrade the antibodies. Addition of protease inhibitors helps to slow degradation.
    储存条件
    -20 °C
    储存方法
    Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.
  • Siddiqui, Horvat-Bröcker, Faissner: "The glia-derived extracellular matrix glycoprotein tenascin-C promotes embryonic and postnatal retina axon outgrowth via the alternatively spliced fibronectin type III domain TNfnD." in: Neuron glia biology, Vol. 4, Issue 4, pp. 271-83, (2010) (PubMed).

    Rigato, Garwood, Calco, Heck, Faivre-Sarrailh, Faissner: "Tenascin-C promotes neurite outgrowth of embryonic hippocampal neurons through the alternatively spliced fibronectin type III BD domains via activation of the cell adhesion molecule F3/contactin." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 22, Issue 15, pp. 6596-609, (2002) (PubMed).

    Bartsch, Bartsch, Dörries, Faissner, Weller, Ekblom, Schachner: "Expression of tenascin in the developing and adult cerebellar cortex." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 12, Issue 3, pp. 736-49, (1992) (PubMed).

    Stern, Norris, Bronner-Fraser, Carlson, Faissner, Keynes, Schachner: "J1/tenascin-related molecules are not responsible for the segmented pattern of neural crest cells or motor axons in the chick embryo." in: Development (Cambridge, England), Vol. 107, Issue 2, pp. 309-19, (1990) (PubMed).

    Gatchalian, Schachner, Sanes: "Fibroblasts that proliferate near denervated synaptic sites in skeletal muscle synthesize the adhesive molecules tenascin(J1), N-CAM, fibronectin, and a heparan sulfate proteoglycan." in: The Journal of cell biology, Vol. 108, Issue 5, pp. 1873-90, (1989) (PubMed).

  • 抗原
    TNC (Tenascin C (TNC))
    别名
    Tenascin-C (TNC 产品)
    别名
    tn antibody, 150-225 antibody, GMEM antibody, GP antibody, HXB antibody, JI antibody, TN antibody, TN-C antibody, AI528729 antibody, C130033P17Rik antibody, Hxb antibody, Ten antibody, cytotactin antibody, tenascin-C antibody, P230 antibody, tenc antibody, wu:fk04d02 antibody, tenascin C L homeolog antibody, tenascin C antibody, tnc.L antibody, TNC antibody, MCYG_00667 antibody, tnc antibody, Tnc antibody
    背景
    Synonyms: TN-C, J1-200/220, Cytoactin
    途径
    Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development
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