RIMS2 抗体 (AA 461-987)
-
- 抗原 See all RIMS2 抗体
- RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))
-
抗原表位
- AA 461-987
- 适用
- 大鼠, 小鼠, 斑马鱼, 小鸡, Hamster
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This RIMS2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- 特异性
- RIM 2 including splice variants
- 交叉反应 (详细)
- cross reactivity to RIM 1.
- 纯化方法
- Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.
- 免疫原
- Recombinant protein (aa 461-987) of rat RIM 2 containing part of PDZ domain.
-
-
- 应用备注
-
WB: 1 : 100 up to 1 : 1000 (AP staining)
IP: not tested yet
ICC: 1 : 200 up to 1 : 500
IHC: 1 : 1000 - 说明
-
This antibody works with paraformaldehyde and methanol fixation.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.
- 缓冲液
- PBS
- 注意事项
- Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.
- 储存条件
- -20 °C
- 储存方法
- Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!
-
-
Bassoon-disruption slows vesicle replenishment and induces homeostatic plasticity at a CNS synapse." in: The EMBO journal, Vol. 33, Issue 5, pp. 512-27, (2014) (PubMed).
: "Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina." in: Molecular vision, Vol. 20, pp. 1422-33, (2014) (PubMed).
: "Inter-channel scaffolding of presynaptic CaV2.2 via the C terminal PDZ ligand domain." in: Biology open, Vol. 2, Issue 5, pp. 492-8, (2013) (PubMed).
: "Molecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release site." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 31, pp. E392-401, (2011) (PubMed).
: "Modulation of Cav1.3 Ca2+ channel gating by Rab3 interacting molecule." in: Molecular and cellular neurosciences, Vol. 44, Issue 3, pp. 246-59, (2010) (PubMed).
: "Molecular anatomy of the hair cell's ribbon synapse." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 37, pp. 12387-99, (2010) (PubMed).
: "Early steps in the assembly of photoreceptor ribbon synapses in the mouse retina: the involvement of precursor spheres." in: The Journal of comparative neurology, Vol. 512, Issue 6, pp. 814-24, (2008) (PubMed).
: "Interaction between Munc13-1 and RIM is critical for glucagon-like peptide-1 mediated rescue of exocytotic defects in Munc13-1 deficient pancreatic beta-cells." in: Diabetes, Vol. 56, Issue 10, pp. 2579-88, (2007) (PubMed).
: "A proteomic screen for presynaptic terminal N-type calcium channel (CaV2.2) binding partners." in: Journal of biochemistry and molecular biology, Vol. 40, Issue 3, pp. 302-14, (2007) (PubMed).
: "ELKS, a protein structurally related to the active zone protein CAST, is involved in Ca2+-dependent exocytosis from PC12 cells." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 11, Issue 6, pp. 659-72, (2006) (PubMed).
: "Differential expression of active zone proteins in neuromuscular junctions suggests functional diversification." in: The European journal of neuroscience, Vol. 24, Issue 11, pp. 3043-52, (2006) (PubMed).
: "Molecular dissection of the photoreceptor ribbon synapse: physical interaction of Bassoon and RIBEYE is essential for the assembly of the ribbon complex." in: The Journal of cell biology, Vol. 168, Issue 5, pp. 825-36, (2005) (PubMed).
: "ELKS, a protein structurally related to the active zone-associated protein CAST, is expressed in pancreatic beta cells and functions in insulin exocytosis: interaction of ELKS with exocytotic ..." in: Molecular biology of the cell, Vol. 16, Issue 7, pp. 3289-300, (2005) (PubMed).
: "
-
Bassoon-disruption slows vesicle replenishment and induces homeostatic plasticity at a CNS synapse." in: The EMBO journal, Vol. 33, Issue 5, pp. 512-27, (2014) (PubMed).
-
- 抗原
- RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))
- 别名
- RIM 2 (RIMS2 产品)
- 别名
- OBOE antibody, RAB3IP3 antibody, RIM2 antibody, 2810036I15Rik antibody, AW048769 antibody, Rab3ip2 antibody, Rim2(+40A) antibody, Rim2(+44A) antibody, Rim2(+4A) antibody, Serg2 antibody, Syt3-rs antibody, mKIAA0751 antibody, Nim2 antibody, Rim2 antibody, RIMS2 antibody, MGC159469 antibody, rims2 antibody, zgc:73064 antibody, drs antibody, drsp antibody, mema antibody, np-a antibody, pinin antibody, pnn antibody, pnn-a antibody, pnn-b antibody, sdk3 antibody, regulating synaptic membrane exocytosis 2 antibody, regulating synaptic membrane exocytosis 2a antibody, pinin, desmosome associated protein S homeolog antibody, RIMS2 antibody, Rims2 antibody, rims2a antibody, pnn.S antibody
- 途径
- Hormone Transport, Synaptic Vesicle Exocytosis
-