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Regulating Synaptic Membrane Exocytosis 1 (RIMS1) (AA 596-705) 抗体

RIMS1 适用: 小鼠, 大鼠, 人, 小鸡, Frog, Hamster WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1742305
发货至: 中国
  • 抗原 See all Regulating Synaptic Membrane Exocytosis 1 (RIMS1) 抗体
    Regulating Synaptic Membrane Exocytosis 1 (RIMS1)
    抗原表位
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 596-705
    适用
    小鼠, 大鼠, 人, 小鸡, Frog, Hamster
    宿主
    • 6
    • 1
    克隆类型
    • 7
    多克隆
    标记
    • 7
    非结合性
    应用范围
    • 7
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    特异性
    Specific for RIM 1
    交叉反应 (详细)
    weak cross reactivity to RIM 2.
    纯化方法
    Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.
    免疫原
    Recombinant protein (aa 596-705) of rat RIM 1 containing part of PDZ domain.
  • 应用备注
    WB: 1 : 100 up to 1 : 1000 (AP staining)
    IP: not tested yet
    ICC: 1 : 200 up to 1 : 500
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.
    缓冲液
    PBS
    注意事项
    Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.
    储存条件
    -20 °C
    储存方法
    Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!
  • Tang, Chen, Li, Metzbower, MacGillavry, Blanpied: "A trans-synaptic nanocolumn aligns neurotransmitter release to receptors." in: Nature, Vol. 536, Issue 7615, pp. 210-4, (2016) (PubMed).

    Grabner, Gandini, Rehak, Le, Zamponi, Schmitz: "RIM1/2-Mediated Facilitation of Cav1.4 Channel Opening Is Required for Ca2+-Stimulated Release in Mouse Rod Photoreceptors." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 38, pp. 13133-47, (2015) (PubMed).

    Fernandes, Riordan, Nomura, Remmers, Kraniotis, Marshall, Kukreja, Vassar, Contractor: "Epac2 Mediates cAMP-Dependent Potentiation of Neurotransmission in the Hippocampus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 16, pp. 6544-53, (2015) (PubMed).

    Ramírez-Franco, Bartolomé-Martín, Alonso, Torres, Sánchez-Prieto: "Cannabinoid type 1 receptors transiently silence glutamatergic nerve terminals of cultured cerebellar granule cells." in: PLoS ONE, Vol. 9, Issue 2, pp. e88594, (2014) (PubMed).

    Wilhelm, Mandad, Truckenbrodt, Kröhnert, Schäfer, Rammner, Koo, Claßen, Krauss, Haucke, Urlaub, Rizzoli: "Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins." in: Science (New York, N.Y.), Vol. 344, Issue 6187, pp. 1023-8, (2014) (PubMed).

    Juranek, Mukherjee, Siddiqui, Kaplan, Li, Ahnert-Hilger, Jahn, Calka: "Active zone protein expression changes at the key stages of cerebellar cortex neurogenesis in the rat." in: Acta histochemica, Vol. 115, Issue 6, pp. 616-25, (2013) (PubMed).

    Bello, Zanetti, Mayorga, Michaut: "RIM, Munc13, and Rab3A interplay in acrosomal exocytosis." in: Experimental cell research, Vol. 318, Issue 5, pp. 478-88, (2012) (PubMed).

    Limbach, Laue, Wang, Hu, Thiede, Hultqvist, Kilimann: "Molecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release site." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 31, pp. E392-401, (2011) (PubMed).

    Leal-Ortiz, Waites, Terry-Lorenzo, Zamorano, Gundelfinger, Garner: "Piccolo modulation of Synapsin1a dynamics regulates synaptic vesicle exocytosis." in: The Journal of cell biology, Vol. 181, Issue 5, pp. 831-46, (2008) (PubMed).

    Regus-Leidig, Tom Dieck, Specht, Meyer, Brandstätter: "Early steps in the assembly of photoreceptor ribbon synapses in the mouse retina: the involvement of precursor spheres." in: The Journal of comparative neurology, Vol. 512, Issue 6, pp. 814-24, (2008) (PubMed).

    Jüttner, Moré, Das, Babich, Meier, Henning, Erdmann, Mu Ller, Otto, Grantyn, Rathjen: "Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity." in: Neuron, Vol. 46, Issue 2, pp. 233-45, (2005) (PubMed).

  • 抗原
    Regulating Synaptic Membrane Exocytosis 1 (RIMS1)
    别名
    RIM 1 (RIMS1 产品)
    别名
    RIMS1 antibody, MGC121671 antibody, C030033M19Rik antibody, RIM1 antibody, RIM1a antibody, RIM1alpha antibody, Rab3ip1 antibody, Rim antibody, Serg1 antibody, mKIAA0340 antibody, CORD7 antibody, RAB3IP2 antibody, RIM antibody, Rim1 antibody, regulating synaptic membrane exocytosis 1 antibody, RIMS1 antibody, rims1 antibody, Rims1 antibody
    途径
    Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
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