Regulating Synaptic Membrane Exocytosis 1 (RIMS1) (AA 596-705) 抗体
(11 references)Quick Overview for Regulating Synaptic Membrane Exocytosis 1 (RIMS1) (AA 596-705) 抗体 (ABIN1742305)
抗原
See all Regulating Synaptic Membrane Exocytosis 1 (RIMS1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 596-705
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特异性
- Specific for RIM 1
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交叉反应 （详细）
- weak cross reactivity to RIM 2.
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纯化方法
- Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.
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免疫原
- Recombinant protein (aa 596-705) of rat RIM 1 containing part of PDZ domain.
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anti-Regulating Synaptic Membrane Exocytosis 1 (RIMS1) (AA 207-366) antibody
RIMS1 适用: 大鼠, 小鼠 WB, ICC, IHC 宿主: 兔 Polyclonal unconjugated
anti-Regulating Synaptic Membrane Exocytosis 1 (RIMS1) (AA 955-1156) antibodyRIMS1 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulating Synaptic Membrane Exocytosis 1 (RIMS1) (AA 1039-1054), (Intracellular) antibodyRIMS1 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1 : 100 up to 1 : 1000 (AP staining)
IP: not tested yet
ICC: 1 : 200 up to 1 : 500 -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.
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缓冲液
- PBS
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注意事项
- Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.
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储存条件
- -20 °C
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储存方法
- Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!
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: "A trans-synaptic nanocolumn aligns neurotransmitter release to receptors." in: Nature, Vol. 536, Issue 7615, pp. 210-4, (2016) (PubMed).
: "RIM1/2-Mediated Facilitation of Cav1.4 Channel Opening Is Required for Ca2+-Stimulated Release in Mouse Rod Photoreceptors." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 38, pp. 13133-47, (2015) (PubMed).
: "Epac2 Mediates cAMP-Dependent Potentiation of Neurotransmission in the Hippocampus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 16, pp. 6544-53, (2015) (PubMed).
: "Cannabinoid type 1 receptors transiently silence glutamatergic nerve terminals of cultured cerebellar granule cells." in: PLoS ONE, Vol. 9, Issue 2, pp. e88594, (2014) (PubMed).
: "Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins." in: Science (New York, N.Y.), Vol. 344, Issue 6187, pp. 1023-8, (2014) (PubMed).
: "Active zone protein expression changes at the key stages of cerebellar cortex neurogenesis in the rat." in: Acta histochemica, Vol. 115, Issue 6, pp. 616-25, (2013) (PubMed).
: "RIM, Munc13, and Rab3A interplay in acrosomal exocytosis." in: Experimental cell research, Vol. 318, Issue 5, pp. 478-88, (2012) (PubMed).
: "Molecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release site." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 31, pp. E392-401, (2011) (PubMed).
: "Piccolo modulation of Synapsin1a dynamics regulates synaptic vesicle exocytosis." in: The Journal of cell biology, Vol. 181, Issue 5, pp. 831-46, (2008) (PubMed).
: "Early steps in the assembly of photoreceptor ribbon synapses in the mouse retina: the involvement of precursor spheres." in: The Journal of comparative neurology, Vol. 512, Issue 6, pp. 814-24, (2008) (PubMed).
: "Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity." in: Neuron, Vol. 46, Issue 2, pp. 233-45, (2005) (PubMed).
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: "A trans-synaptic nanocolumn aligns neurotransmitter release to receptors." in: Nature, Vol. 536, Issue 7615, pp. 210-4, (2016) (PubMed).
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- Regulating Synaptic Membrane Exocytosis 1 (RIMS1)
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别名
- RIM 1
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途径
- Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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