SV2B 抗体 (AA 2-17)
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- 抗原 See all SV2B 抗体
- SV2B (Synaptic Vesicle Glycoprotein 2B (SV2B))
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抗原表位
- AA 2-17
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适用
- 人, 小鼠, 大鼠, Hamster, 小鸡
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SV2B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
- 特异性
- Specific for SV2 B.
- 纯化方法
- antiserum
- 免疫原
- Synthetic peptide DDYRYRDNYEGYAPND (aa 2-17 in rat) coupled to key-hole limpet hemocyanin via an added N-terminal cysteine residue.
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- 应用备注
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WB: 1 : 1000 (AP staining)
ICC: 1 : 200 - 说明
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WB: SV2 aggregates after boiling, making it necessary to run SDS-PAGE only with non-boiled samples.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS
- 注意事项
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Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4 °C.
Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20 °C),however, is preferable. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.
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SV2B is essential for the integrity of the glomerular filtration barrier." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 95, Issue 5, pp. 534-45, (2015) (PubMed).
: "Expression pattern of synaptic vesicle protein 2 (SV2) isoforms in patients with temporal lobe epilepsy and hippocampal sclerosis." in: Neuropathology and applied neurobiology, Vol. 40, Issue 2, pp. 191-204, (2014) (PubMed).
: "Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting." in: The EMBO journal, Vol. 33, Issue 2, pp. 157-70, (2014) (PubMed).
: "Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E." in: The Biochemical journal, Vol. 453, Issue 1, pp. 37-47, (2013) (PubMed).
: "Expression of SV2 isoforms during rodent brain development." in: BMC neuroscience, Vol. 14, pp. 87, (2013) (PubMed).
: "Preferential entry of botulinum neurotoxin A Hc domain through intestinal crypt cells and targeting to cholinergic neurons of the mouse intestine." in: PLoS pathogens, Vol. 8, Issue 3, pp. e1002583, (2012) (PubMed).
: "Extensive remodeling of the presynaptic cytomatrix upon homeostatic adaptation to network activity silencing." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 28, pp. 10189-200, (2011) (PubMed).
: "Cortico-hippocampal hyperexcitability in synapsin I/II/III knockout mice: age-dependency and response to the antiepileptic drug levetiracetam." in: Neuroscience, Vol. 171, Issue 1, pp. 268-83, (2010) (PubMed).
: "SV2 mediates entry of tetanus neurotoxin into central neurons." in: PLoS pathogens, Vol. 6, Issue 11, pp. e1001207, (2010) (PubMed).
: "Loss of the Synaptic Vesicle Protein SV2B results in reduced neurotransmission and altered synaptic vesicle protein expression in the retina." in: PLoS ONE, Vol. 4, Issue 4, pp. e5230, (2009) (PubMed).
: "Receptor-mediated transcytosis of botulinum neurotoxin A through intestinal cell monolayers." in: Cellular microbiology, Vol. 10, Issue 2, pp. 375-87, (2008) (PubMed).
: "Traffic of botulinum toxins A and E in excitatory and inhibitory neurons." in: Traffic (Copenhagen, Denmark), Vol. 8, Issue 2, pp. 142-53, (2007) (PubMed).
: "Synaptic vesicle protein 2B is expressed in podocyte, and its expression is altered in proteinuric glomeruli." in: Journal of the American Society of Nephrology : JASN, Vol. 17, Issue 10, pp. 2748-59, (2006) (PubMed).
: "SV2A and SV2C contain a unique synaptotagmin-binding site." in: Molecular and cellular neurosciences, Vol. 29, Issue 1, pp. 56-64, (2005) (PubMed).
: "The expression pattern and assembly profile of synaptic membrane proteins in ribbon synapses of the developing mouse retina." in: Cell and tissue research, Vol. 311, Issue 2, pp. 159-73, (2003) (PubMed).
: "Brain synaptic junctional proteins at the acrosome of rat testicular germ cells." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 51, Issue 6, pp. 809-19, (2003) (PubMed).
: "SV2C is a synaptic vesicle protein with an unusually restricted localization: anatomy of a synaptic vesicle protein family." in: Neuroscience, Vol. 94, Issue 4, pp. 1279-90, (2000) (PubMed).
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SV2B is essential for the integrity of the glomerular filtration barrier." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 95, Issue 5, pp. 534-45, (2015) (PubMed).
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- 抗原
- SV2B (Synaptic Vesicle Glycoprotein 2B (SV2B))
- 别名
- SV2 B (SV2B 产品)
- 别名
- SV2B antibody, A830038F04Rik antibody, AI850768 antibody, mKIAA0735 antibody, HsT19680 antibody, synaptic vesicle glycoprotein 2B antibody, synaptic vesicle glycoprotein 2 b antibody, synaptic vesicle glycoprotein 2b antibody, SV2B antibody, CpipJ_CPIJ009611 antibody, Sv2b antibody
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