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- 抗原
- pADPR
- 适用
- 所有种类
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- Agarose Beads
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应用范围
- Immunoprecipitation (IP)
- 产品特性
- Recognizes DNA-damage and apoptosis related poly-ADP ribosylated proteins and poly (ADP-ribose) polymer
- 纯化方法
- Protein A affinity column
- 免疫原
- poly(ADP-ribose)
- 克隆位点
- 10H
- 亚型
- IgG3
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- 应用备注
- 0.5 µg/IP reaction
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS, pH 7.4 with 0,05 % sodium azides
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze/thaw cycles.
- 储存条件
- 4 °C
- 储存方法
- Stable for 1 year from date of shipment when stored at -20 °C or -70 °C. Stable for at least 1 month at 4 °C.
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Involvement of poly(ADP-Ribose) polymerase 1 and poly(ADP-Ribosyl)ation in regulation of centrosome function." in: Molecular and cellular biology, Vol. 23, Issue 7, pp. 2451-62, (2003) (PubMed).
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Involvement of poly(ADP-Ribose) polymerase 1 and poly(ADP-Ribosyl)ation in regulation of centrosome function." in: Molecular and cellular biology, Vol. 23, Issue 7, pp. 2451-62, (2003) (PubMed).
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- 抗原
- pADPR
- 背景
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Synonyms: poly(ADP-ribose)
Poly(ADP-ribose) or pADPr is a polymer synthesized by a class of enzymes named poly(ADP-ribose) polymerase (PARP). Using NAD+ as substrate, PARP catalyzes the formation of the polymer pADPr, with chain lengths ranging from 2 to 300 residues, containing approximately 2 % branching in the chain. pADPr becomes attached to nuclear proteins, and to PARP itself (automodification).
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