KCNK3 抗体 (AA 251-411)
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- 抗原 See all KCNK3 抗体
- KCNK3 (Potassium Channel, Subfamily K, Member 3 (KCNK3))
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抗原表位
- AA 251-411
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This KCNK3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- Detects ~50 kDa. Does not cross-react with TASK3.
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Protein G Purified
- 免疫原
- Fusion protein amino acids 251-411 (cytoplasmic C-terminus) of rat Acid-sensitive potassium channel protein TASK or TASK1. Mouse: 96% identity (156/161 amino acids identical). Human: 76% identity (163/161 amino acids identical). <30% identity with TASK3.
- 克隆位点
- S374-48
- 亚型
- IgG2b
- Top Product
- Discover our top product KCNK3 Primary Antibody
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- 应用备注
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- 说明
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1 μg/ml of ABIN1741485 was sufficient for detection of TASK1 Potassium Channel in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C
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- 抗原
- KCNK3 (Potassium Channel, Subfamily K, Member 3 (KCNK3))
- 别名
- KCNK3 (KCNK3 产品)
- 别名
- si:dkey-164m15.1 antibody, K2p3.1 antibody, OAT1 antibody, PPH4 antibody, TASK antibody, TASK-1 antibody, TBAK1 antibody, cTBAK-1 antibody, Task-1 antibody, rTASK antibody, KCNK3 antibody, potassium channel, subfamily K, member 3a antibody, potassium two pore domain channel subfamily K member 3 antibody, potassium channel, subfamily K, member 3 antibody, kcnk3a antibody, KCNK3 antibody, Kcnk3 antibody
- 背景
- K+ channels are divided into three subclasses reflecting the number of transmembrane segments (TMS), which are designated 6TMS, 4TMS and 2TMS. Members of the 4TMS class contain two distinct pore regions and include TWIK, TREK, TRAAK and TASK. TASK channels are highly sensitive to external pH in the physiological range. TASK-1 is expressed in brain and in rat heart, with high levels of expression in the right atrium. TASK-2, mainly expressed in kidney, is localized in cortical distal tubules and collecting ducts, suggesting a role in renal K+ transport. TASK-3 from rat cerebellum shares 54 % identity with TASK-1, but less than 30 % identity with TASK-2 and other tandem pore K+ channels.
- 基因ID
- 29553
- NCBI登录号
- NP_203694
- UniProt
- O54912
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