Neuroligin 1 抗体 (AA 718-843)
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- 抗原 See all Neuroligin 1 (NLGN1) 抗体
- Neuroligin 1 (NLGN1)
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抗原表位
- AA 718-843
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Neuroligin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- Detects ~120 kDa. Does not cross-react with other Neuroligins.
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Protein G Purified
- 免疫原
- Fusion protein amino acids 718-843 (cytoplasmic C-terminus) of rat Neuroligin-1. Mouse: 99% identity (125/126 amino acids identical). Human: 99% identity (125/126 amino acids identical) >40% identity with Neuroligin-2 and -3.
- 克隆位点
- S97A-31
- 亚型
- IgG1
- Top Product
- Discover our top product NLGN1 Primary Antibody
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- 应用备注
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- 说明
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2 μg/ml of ABIN1741305 was sufficient for detection of Neuroligin-1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C
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- 抗原
- Neuroligin 1 (NLGN1)
- 别名
- Neuroligin 1 (NLGN1 产品)
- 别名
- NLGN1 antibody, Nlgn1 antibody, GB18720 antibody, nlgn1 antibody, NL1 antibody, 6330415N05Rik antibody, BB179718 antibody, mKIAA1070 antibody, neuroligin-1 antibody, neuroligin 1 antibody, NLGN1 antibody, LOC659779 antibody, LOC724358 antibody, nlgn1 antibody, Nlgn1 antibody
- 背景
- Neuroligin-1 is a neuronal cell surface protein belonging to the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of excitatory synapses for their normal, functional development, and is necessary to the regulation of synaptic plasticity and the development of long-term memory within the adult amygdala in mammals. It is believed to participate in cell-cell-interaction through the assembly of intracellular junction by the binding of beta-neurexins, and may also be a factor in the maintenance and assembly of synaptic junctions. It is also thought to have involvement in excitatory synaptic specification. Within brain tissue, Neuroligin-1 is primarily observed in neurons and spinal cord.
- 基因ID
- 116647
- UniProt
- Q62765
- 途径
- Synaptic Membrane, Synaptic Vesicle Exocytosis
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