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LGI1 抗体 (AA 37-113) (Atto 390)

LGI1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S283-7 Atto 390
产品编号 ABIN1741270
发货至: 中国
  • 抗原 See all LGI1 抗体
    LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))
    抗原表位
    • 18
    • 15
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 37-113
    适用
    • 42
    • 24
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 27
    • 21
    小鼠
    克隆类型
    • 28
    • 20
    单克隆
    标记
    • 19
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LGI1 antibody is conjugated to Atto 390
    应用范围
    • 47
    • 21
    • 15
    • 13
    • 13
    • 13
    • 12
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Detects ~60 kDa.
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Protein G Purified
    免疫原
    Fusion protein amino acids 37-113 (LRRNT domain and first LRR repeat) of mouse LGI1. Rat: 100% identity (77/77 amino acids identical). Human: 98% identity (76/77 amino acids identical). ~50% identity with LGI2, LGI3 and LGI4.
    克隆位点
    S283-7
    亚型
    IgG2a
    Top Product
    Discover our top product LGI1 Primary Antibody
  • 应用备注
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    说明

    1 μg/ml of ABIN1741270 was sufficient for detection of LGI1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Conjugated antibodies should be stored at 4°C
  • 抗原
    LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))
    别名
    LGI1 (LGI1 产品)
    别名
    ADLTE antibody, ADPAEF antibody, ADPEAF antibody, EPITEMPIN antibody, EPT antibody, ETL1 antibody, IB1099 antibody, BB130740 antibody, MGC146600 antibody, LGIa antibody, fb78h12 antibody, wu:fb78h12 antibody, zgc:65886 antibody, leucine rich glioma inactivated 1 antibody, leucine-rich repeat LGI family, member 1 antibody, leucine-rich, glioma inactivated 1 antibody, leucine-rich, glioma inactivated 1b antibody, leucine-rich, glioma inactivated 1a antibody, LGI1 antibody, Lgi1 antibody, lgi1 antibody, lgi1b antibody, lgi1a antibody
    背景
    The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist, this LGI1 antibody will recognize only the longer form.
    基因ID
    56839
    NCBI登录号
    NP_064674
    UniProt
    Q9JIA1
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