GFAP 抗体 (AA 411-422) (FITC)
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- 抗原 See all GFAP 抗体
- GFAP (Glial Fibrillary Acidic Protein (GFAP))
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抗原表位
- AA 411-422
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This GFAP antibody is conjugated to FITC
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Detects ~50 kDa. Cross-reacts with GFAP-R416W and other GFAP mutant proteins.
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Protein G Purified
- 免疫原
- Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP, 100% identical in rat and mouse
- 克隆位点
- S206A-8
- 亚型
- IgG1
- Top Product
- Discover our top product GFAP Primary Antibody
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- 应用备注
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- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
- 说明
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1 μg/ml of ABIN1740957 was sufficient for detection of GFAP in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Conjugated antibodies should be stored at 4°C
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- 抗原
- GFAP (Glial Fibrillary Acidic Protein (GFAP))
- 别名
- GFAP (GFAP 产品)
- 别名
- GFAP antibody, AI836096 antibody, cb345 antibody, etID36982.3 antibody, gfapl antibody, wu:fb34h11 antibody, wu:fk42c12 antibody, xx:af506734 antibody, zgc:110485 antibody, glial fibrillary acidic protein antibody, GFAP antibody, LOC100136168 antibody, gfap antibody, Gfap antibody
- 背景
- The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia.
- 基因ID
- 2670
- NCBI登录号
- NP_001124491
- UniProt
- P14136
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