Nibrin 抗体 (AA 467-615)
(2 references)-
- 抗原 See all Nibrin (NBN) 抗体
- Nibrin (NBN)
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抗原表位
- AA 467-615
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Nibrin antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 原理
- NBN Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human NBN (AA: 467-615) expressed in E. Coli.
- 克隆位点
- 7E4A2
- 亚型
- IgG2a
- Top Product
- Discover our top product NBN Primary Antibody
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anti-Nibrin (NBN) (AA 467-615) antibody
NBN 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 7E4C2 unconjugated
anti-Nibrin (NBN) (AA 461-754) antibodyNBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3A2 unconjugated
anti-Nibrin (NBN) (AA 461-754) antibodyNBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Nibrin (NBN) (AA 183-460) antibodyNBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 8E7 unconjugated
anti-Nibrin (NBN) (AA 183-460) antibodyNBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2F5 unconjugated
anti-Nibrin (NBN) (AA 183-460) antibodyNBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 6E11 unconjugated
anti-Nibrin (NBN) (AA 435-754) antibodyNBN 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nibrin (NBN) (AA 645-754) antibodyNBN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E4 unconjugated
anti-Nibrin (NBN) antibodyKO Validated NBN 适用: 人 WB, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Nibrin (NBN) (AA 714-745), (C-Term) antibodyNBN 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Identification of a novel NBN truncating mutation in a family with hereditary prostate cancer." in: Familial cancer, Vol. 11, Issue 4, pp. 595-600, (2012) (PubMed).
: "Functional NBS1 polymorphism is associated with occurrence and advanced disease status of nasopharyngeal carcinoma." in: Molecular carcinogenesis, Vol. 50, Issue 9, pp. 689-96, (2011) (PubMed).
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: "Identification of a novel NBN truncating mutation in a family with hereditary prostate cancer." in: Familial cancer, Vol. 11, Issue 4, pp. 595-600, (2012) (PubMed).
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- 抗原
- Nibrin (NBN)
- 别名
- NBN (NBN 产品)
- 别名
- NBN antibody, AT-V1 antibody, AT-V2 antibody, ATV antibody, NBS antibody, NBS1 antibody, P95 antibody, Nbs1 antibody, im:6911679 antibody, zgc:194152 antibody, nibrin antibody, NBN antibody, nbn antibody, Nbn antibody
- 背景
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Description: Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Aliases: ATV, NBS, P95, NBS1, AT-V1, AT-V2
- 分子量
- 85kDa
- 基因ID
- 4683
- HGNC
- 4683
- UniProt
- O60934
- 途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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