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Nibrin 抗体 (AA 467-615)

Name: Nibrin 抗体 (AA 467-615)
Brand: antibodies-online
SKU: ABIN1724946
Availability: OutOfStock

NBN 适用: 人, 大鼠 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 7E4A2 unconjugated

Western blot analysis using NBN mouse mAb against A549 (1), Jurkat (2) and PC-12 (3) cell lysate. (Nibrin 抗体 (AA 467-615))

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (Nibrin 抗体 (AA 467-615))

ELISA

Flow cytometric analysis of Hela cells using NBN mouse mAb (green) and negative control (red). (Nibrin 抗体 (AA 467-615))

FACS

Immunofluorescence analysis of Hela cells using NBN mouse mAb (green). (Nibrin 抗体 (AA 467-615))

Western blot analysis using NBN mAb against human NBN (AA: 467-615) recombinant protein. (Nibrin 抗体 (AA 467-615))

Western blot analysis using NBN mAb against HEK293 (1) and NBN (AA: 467-615)-hIgGFc transfected HEK293 (2) cell lysate. (Nibrin 抗体 (AA 467-615))

Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using NBN mouse mAb with DAB staining. (Nibrin 抗体 (AA 467-615))

IHC

Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using NBN mouse mAb with DAB staining. (Nibrin 抗体 (AA 467-615))

IHC

8 images

(2 references)

产品编号 ABIN1724946

发货至: 中国

Datasheet as PDF

抗原 See all Nibrin (NBN) 抗体

Nibrin (NBN)
抗原表位
37

15

12

8

7

5

4

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 467-615
适用
100

60

36

2

1

1

1

1
人, 大鼠
宿主
118

14
小鼠
Compatible Secondaries
克隆类型
109

23
单克隆
标记
66

8

5

4

4

4

4

4

4

3

2

2

2

2

2

2

2

2

2

2

2

2

2
This Nibrin antibody is un-conjugated
应用范围
103

46

28

27

26

25

23

16

8

8

6

4

2

2

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

纯化方法

purified

免疫原

Purified recombinant fragment of human NBN (AA: 467-615) expressed in E. coli.

克隆位点

7E4A2

亚型

IgG2a
anti-Nibrin (NBN) (AA 467-615) antibody
NBN 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 7E4C2 unconjugated

anti-Nibrin (NBN) (AA 461-754) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3A2 unconjugated

anti-Nibrin (NBN) (AA 461-754) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3A9 unconjugated

anti-Nibrin (NBN) (AA 183-460) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 8E7 unconjugated

anti-Nibrin (NBN) (AA 183-460) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2F5 unconjugated

anti-Nibrin (NBN) (AA 183-460) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 6E11 unconjugated

anti-Nibrin (NBN) (AA 435-754) antibody
NBN 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Nibrin (NBN) (AA 645-754) antibody
NBN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E4 unconjugated

anti-Nibrin (NBN) antibody
KO Validated NBN 适用: 人 WB, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Nibrin (NBN) (AA 714-745), (C-Term) antibody
NBN 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

限制

仅限研究用
状态

Liquid

缓冲液

Purified antibody in PBS with 0.05 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

4°C, -20°C for long term storage
Zuhlke, Johnson, Okoth, Stoffel, Robbins, Tembe, Salinas, Zheng, Xu, Carpten, Lange, Isaacs, Cooney: "Identification of a novel NBN truncating mutation in a family with hereditary prostate cancer." in: Familial cancer, Vol. 11, Issue 4, pp. 595-600, (2012) (PubMed).

Zheng, Zhang, Jiang, You, Liu, Lu, Zhou: "Functional NBS1 polymorphism is associated with occurrence and advanced disease status of nasopharyngeal carcinoma." in: Molecular carcinogenesis, Vol. 50, Issue 9, pp. 689-96, (2011) (PubMed).
抗原

Nibrin (NBN)

别名

NBN (NBN 产品)

别名

NBN antibody, AT-V1 antibody, AT-V2 antibody, ATV antibody, NBS antibody, NBS1 antibody, P95 antibody, Nbs1 antibody, im:6911679 antibody, zgc:194152 antibody, nibrin antibody, NBN antibody, nbn antibody, Nbn antibody

背景

Description: Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Aliases: ATV, NBS, P95, NBS1, AT-V1, AT-V2

分子量

85 kDa

基因ID

4683

HGNC

4683

途径

DNA Damage Repair, Production of Molecular Mediator of Immune Response