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TRF2 抗体 (AA 324-500)

TERF2 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 3H6B4 unconjugated
产品编号 ABIN1724941
发货至: 中国
  • 抗原 See all TRF2 (TERF2) 抗体
    TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))
    抗原表位
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 324-500
    适用
    • 39
    • 10
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 34
    • 4
    • 2
    小鼠
    克隆类型
    • 37
    • 3
    单克隆
    标记
    • 22
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRF2 antibody is un-conjugated
    应用范围
    • 29
    • 20
    • 18
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    原理
    TERF2 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human TERF2 (AA: 324-500) expressed in E. Coli.
    克隆位点
    3H6B4
    亚型
    IgG1
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Galati, Magdinier, Colasanti, Bauwens, Pinte, Ricordy, Giraud-Panis, Pusch, Savino, Cacchione, Gilson: "TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner." in: PLoS ONE, Vol. 7, Issue 4, pp. e34386, (2012) (PubMed).

    Diehl, Idowu, Kimmelshue, York, Jackson-Cook, Turner, Holt, Elmore: "Elevated TRF2 in advanced breast cancers with short telomeres." in: Breast cancer research and treatment, Vol. 127, Issue 3, pp. 623-30, (2011) (PubMed).

  • 抗原
    TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))
    别名
    TERF2 (TERF2 产品)
    别名
    TERF2 antibody, TRBF2 antibody, TRF2 antibody, trf2 antibody, telomeric repeat binding factor 2 antibody, telomeric repeat binding factor 2 L homeolog antibody, TERF2 antibody, Terf2 antibody, terf2.L antibody
    背景

    Description: This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.


    Aliases: TRF2, TRBF2

    分子量
    55.6kDa
    基因ID
    7014
    HGNC
    7014
    UniProt
    Q15554
    途径
    Cell Division Cycle, Telomere Maintenance
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