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Syndecan 1 抗体 (AA 28-171)

SDC1 适用: 人 WB, ELISA, FACS, IHC, ICC 宿主: 小鼠 Monoclonal 1A3H4 unconjugated
产品编号 ABIN1724936
发货至: 中国
  • 抗原 See all Syndecan 1 (SDC1) 抗体
    Syndecan 1 (SDC1)
    抗原表位
    • 16
    • 8
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 28-171
    适用
    • 104
    • 44
    • 33
    • 17
    • 5
    宿主
    • 73
    • 35
    • 3
    • 1
    小鼠
    克隆类型
    • 62
    • 50
    单克隆
    标记
    • 50
    • 12
    • 8
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Syndecan 1 antibody is un-conjugated
    应用范围
    • 64
    • 38
    • 33
    • 24
    • 14
    • 13
    • 11
    • 10
    • 10
    • 9
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    原理
    SDC1 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human SDC1 (AA: 28-171) expressed in E. Coli.
    克隆位点
    1A3H4
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Nunez, Siegal, Reddy, Wei: "CD138 (syndecan-1) expression in bone-forming tumors." in: American journal of clinical pathology, Vol. 137, Issue 3, pp. 423-8, (2012) (PubMed).

    Karasneh, Ali, Shukla: "An important role for syndecan-1 in herpes simplex virus type-1 induced cell-to-cell fusion and virus spread." in: PLoS ONE, Vol. 6, Issue 9, pp. e25252, (2011) (PubMed).

  • 抗原
    Syndecan 1 (SDC1)
    别名
    SDC1 (SDC1 产品)
    背景

    Description: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.




    Aliases: SDC, CD138, SYND1, syndecan

    分子量
    32.5kDa
    基因ID
    6382
    HGNC
    6382
    UniProt
    P18827
    途径
    Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism
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