Syndecan 1 抗体 (AA 28-171)
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- 抗原 See all Syndecan 1 (SDC1) 抗体
- Syndecan 1 (SDC1)
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抗原表位
- AA 28-171
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Syndecan 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- 原理
- SDC1 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human SDC1 (AA: 28-171) expressed in E. Coli.
- 克隆位点
- 1A3H4
- 亚型
- IgG1
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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CD138 (syndecan-1) expression in bone-forming tumors." in: American journal of clinical pathology, Vol. 137, Issue 3, pp. 423-8, (2012) (PubMed).
: "An important role for syndecan-1 in herpes simplex virus type-1 induced cell-to-cell fusion and virus spread." in: PLoS ONE, Vol. 6, Issue 9, pp. e25252, (2011) (PubMed).
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CD138 (syndecan-1) expression in bone-forming tumors." in: American journal of clinical pathology, Vol. 137, Issue 3, pp. 423-8, (2012) (PubMed).
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- 抗原
- Syndecan 1 (SDC1)
- 别名
- SDC1 (SDC1 产品)
- 背景
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Description: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
Aliases: SDC, CD138, SYND1, syndecan
- 分子量
- 32.5kDa
- 基因ID
- 6382
- HGNC
- 6382
- UniProt
- P18827
- 途径
- Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism
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