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beta-2 Microglobulin 抗体 (AA 21-100)

B2M 适用: 人 WB, FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 3G5H8 unconjugated
产品编号 ABIN1724930
发货至: 中国
  • 抗原 See all beta-2 Microglobulin (B2M) 抗体
    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
    抗原表位
    • 19
    • 17
    • 15
    • 5
    • 5
    • 5
    • 5
    • 3
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    • 2
    • 1
    • 1
    • 1
    • 1
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    AA 21-100
    适用
    • 205
    • 51
    • 30
    • 27
    • 10
    • 4
    • 4
    • 4
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    • 2
    • 2
    • 1
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    宿主
    • 123
    • 111
    • 9
    • 6
    • 2
    • 1
    小鼠
    克隆类型
    • 126
    • 125
    • 1
    单克隆
    标记
    • 111
    • 32
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    • 7
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This beta-2 Microglobulin antibody is un-conjugated
    应用范围
    • 127
    • 106
    • 75
    • 66
    • 59
    • 41
    • 40
    • 31
    • 26
    • 18
    • 17
    • 15
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)
    原理
    B2M Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human B2M (AA: 21-100) expressed in E. Coli.
    克隆位点
    3G5H8
    亚型
    IgG2a
    Top Product
    Discover our top product B2M Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Bernal, Ruiz-Cabello, Concha, Paschen, Garrido: "Implication of the ?2-microglobulin gene in the generation of tumor escape phenotypes." in: Cancer immunology, immunotherapy : CII, Vol. 61, Issue 9, pp. 1359-71, (2012) (PubMed).

    Hermansen, Hummelshøj, Lundsgaard, Hornum, Keller, Fleckner, Fox, Poulsen, Jacobsen: "Increased serum ?2-microglobulin is associated with clinical and immunological markers of disease activity in systemic lupus erythematosus patients." in: Lupus, Vol. 21, Issue 10, pp. 1098-104, (2012) (PubMed).

  • 抗原
    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
    别名
    B2M (B2M 产品)
    别名
    Ly-m11 antibody, beta2-m antibody, beta2m antibody, bwm antibody, wu:fa94c05 antibody, wu:fb10a09 antibody, b2m-W01 antibody, b2m-W03 antibody, b2m-Z01 antibody, b2m-Z02 antibody, b2m-Z03 antibody, B2M antibody, b2m antibody, B2MG antibody, wu:fb66f11 antibody, wu:fj01f08 antibody, zgc:64161 antibody, b-2-m antibody, beta-2-microglobulin antibody, beta-2 microglobulin antibody, beta-2-microglobulin S homeolog antibody, beta-2-microglobulin, like antibody, B2M antibody, B2m antibody, b2m antibody, b2m.S antibody, b2ml antibody
    背景
    This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
    分子量
    13.7kDa
    基因ID
    567
    HGNC
    567
    UniProt
    P61769
    途径
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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