MLXIPL 抗体 (AA 18-143)
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- 抗原 See all MLXIPL 抗体
- MLXIPL (MLX Interacting Protein-Like (MLXIPL))
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抗原表位
- AA 18-143
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MLXIPL antibody is un-conjugated
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应用范围
- ELISA, Immunocytochemistry (ICC)
- 原理
- MLXIPL Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human MLXIPL (AA: 18-143) expressed in E. Coli.
- 克隆位点
- 5D12D1
- 亚型
- IgG1
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- 应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Glucose-induced nuclear shuttling of ChREBP is mediated by sorcin and Ca(2+) ions in pancreatic β-cells." in: Diabetes, Vol. 61, Issue 3, pp. 574-85, (2012) (PubMed).
: "ChREBP expression in the liver, adipose tissue and differentiated preadipocytes in human obesity." in: Biochimica et biophysica acta, Vol. 1811, Issue 12, pp. 1194-200, (2011) (PubMed).
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Glucose-induced nuclear shuttling of ChREBP is mediated by sorcin and Ca(2+) ions in pancreatic β-cells." in: Diabetes, Vol. 61, Issue 3, pp. 574-85, (2012) (PubMed).
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- 抗原
- MLXIPL (MLX Interacting Protein-Like (MLXIPL))
- 别名
- MLXIPL (MLXIPL 产品)
- 背景
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Description: This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.
Aliases: MIO, CHREBP, MONDOB, WBSCR14, WS-bHLH, bHLHd14
- 分子量
- 93.1kDa
- 基因ID
- 51085
- HGNC
- 51085
- UniProt
- Q9NP71
- 途径
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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