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Transferrin Receptor 抗体 (AA 608-727)

Name: Transferrin Receptor 抗体 (AA 608-727)
Brand: antibodies-online
SKU: ABIN1724899
Availability: OutOfStock

TFRC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A1B2 unconjugated

Western blot analysis using TFRC mouse mAb against Jurkat (1), Hela (2), K562 (3), Cos7 (4), MCF-7 (5), PC-12 (6), NIH/3T3 (7), HEK293 (8), RAJI (9) cell lysate. (Transferrin Receptor 抗体 (AA 608-727))

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (Transferrin Receptor 抗体 (AA 608-727))

ELISA

Western blot analysis using TFRC mAb against human TFRC recombinant protein. (Transferrin Receptor 抗体 (AA 608-727))

Western blot analysis using TFRC mAb against HEK293 (1) and TFRC (AA: 608-727)-hIgGFc transfected HEK293 (2) cell lysate. (Transferrin Receptor 抗体 (AA 608-727))

4 images

(2 references)

产品编号 ABIN1724899

发货至: 中国

Datasheet as PDF

抗原 See all Transferrin Receptor (TFRC) 抗体

Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
抗原表位
16

14

11

8

8

7

6

6

6

5

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 608-727
适用
192

83

26

7

5

4

2

2

2

1

1

1

1
人
宿主
112

102

29

1

1
小鼠
Compatible Secondaries
克隆类型
143

100

1
单克隆
标记
107

27

21

14

10

5

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Transferrin Receptor antibody is un-conjugated
应用范围
140

133

72

70

49

37

23

19

18

12

7

6

3

3

3

2

2

2

1

1

1

1

1

1

1
Western Blotting (WB), ELISA

原理

TFRC Antibody

纯化方法

Purified antibody

免疫原

Purified recombinant fragment of human TFRC (AA: 608-727) expressed in E. Coli.

克隆位点

1A1B2

亚型

IgG1

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anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 567-744) antibody
TFRC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 572-757) antibody
TFRC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 567-744) antibody
TFRC 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal unconjugated

应用备注

ELISA: 1/10000

限制

仅限研究用
状态

Liquid

缓冲液

Purified antibody in PBS with 0.05 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Płoszyńska, Ruckemann-Dziurdzińska, Jóźwik, Mikosik, Lisowska, Balcerska, Witkowski: "Cytometric evaluation of transferrin receptor 1 (CD71) in childhood acute lymphoblastic leukemia." in: Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society, Vol. 50, Issue 2, pp. 304-11, (2012) (PubMed).

Jian, Yang, Huang: "Src regulates Tyr(20) phosphorylation of transferrin receptor-1 and potentiates breast cancer cell survival." in: The Journal of biological chemistry, Vol. 286, Issue 41, pp. 35708-15, (2011) (PubMed).
抗原

Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

别名

TFRC (TFRC 产品)

别名

Trfr antibody, LOC100219280 antibody, tfr antibody, cd71 antibody, tfr1 antibody, trfr antibody, CD71 antibody, T9 antibody, TFR antibody, TFR1 antibody, TR antibody, TRFR antibody, p90 antibody, 2610028K12Rik antibody, AI195355 antibody, AI426448 antibody, AU015758 antibody, E430033M20Rik antibody, Mtvr-1 antibody, Mtvr1 antibody, transferrin receptor antibody, TFRC antibody, Tfrc antibody, tfrc antibody

背景

Description: Transferrin receptor is a carrier protein for transferrin. It is needed for the import of iron into the cell and is regulated in response to intracellular iron concentration. Low iron concentrations promote increased levels of transferrin receptor, to increase iron intake into the cell. Thus, transferrin receptor maintains cellular iron homeostasis. Expression of human TFR1, but not human TFR2, in hamster cell lines markedly enhanced the infection of viruses pseudotyped with the glycoprotein of Machupo, Guanarito, and Junin viruses, but not with those of Lassa or lymphocytic choriomeningitis viruses. An anti-TFR1 antibody efficiently inhibited the replication of Machupo, Guanarito, Junin, and Sabia viruses, but not that of Lassa virus.TFR1 is a cellular receptor for New World hemorrhagic fever arenaviruses.

Aliases: T9, TR, TFR, p90, CD71, TFR1, TRFR

分子量

85kDa

基因ID

7037

HGNC

7037

UniProt

P02786

途径

Transition Metal Ion Homeostasis