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Dynamin 1-Like 抗体 (AA 69-213)

DNM1L 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 4E11B11 unconjugated
产品编号 ABIN1724863
发货至: 中国
  • 抗原 See all Dynamin 1-Like (DNM1L) 抗体
    Dynamin 1-Like (DNM1L)
    抗原表位
    • 23
    • 11
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 69-213
    适用
    • 57
    • 51
    • 34
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 66
    • 6
    小鼠
    克隆类型
    • 66
    • 6
    单克隆
    标记
    • 31
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Dynamin 1-Like antibody is un-conjugated
    应用范围
    • 32
    • 27
    • 17
    • 13
    • 13
    • 11
    • 9
    • 9
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    原理
    DNM1L Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human DNM1L (AA: 69-213) expressed in E. Coli.
    克隆位点
    4E11B11
    亚型
    IgG1
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Thomas, Jacobson: "Defects in mitochondrial fission protein dynamin-related protein 1 are linked to apoptotic resistance and autophagy in a lung cancer model." in: PLoS ONE, Vol. 7, Issue 9, pp. e45319, (2012) (PubMed).

    Marsboom, Toth, Ryan, Hong, Wu, Fang, Thenappan, Piao, Zhang, Pogoriler, Chen, Morrow, Weir, Rehman, Archer: "Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension." in: Circulation research, Vol. 110, Issue 11, pp. 1484-97, (2012) (PubMed).

  • 抗原
    Dynamin 1-Like (DNM1L)
    别名
    DNM1L (DNM1L 产品)
    别名
    DLP1 antibody, DRP1 antibody, DVLP antibody, DYMPLE antibody, EMPF antibody, HDYNIV antibody, 6330417M19Rik antibody, AI450666 antibody, Dlp1 antibody, Dnmlp1 antibody, Drp1 antibody, python antibody, Dnml1 antibody, dnm1l antibody, MGC53850 antibody, zgc:66163 antibody, DNM1L antibody, 18.m06247 antibody, CG3210 antibody, DRP antibody, Dmel\CG3210 antibody, Dnm1/Drp1 antibody, Drp antibody, Drp-1 antibody, drp-1 antibody, drp1 antibody, frat antibody, l(2)22Fc antibody, l(2)22Fd antibody, l(2)ND2 antibody, l(2)ND3 antibody, dynamin 1 like antibody, dynamin 1-like antibody, dynamin 1-like L homeolog antibody, dynamin-1-like antibody, dynamin-1-like protein antibody, dynamin-like protein antibody, Dynamin related protein 1 antibody, DNM1L antibody, Dnm1l antibody, dnm1l.L antibody, dnm1l antibody, LOC100369408 antibody, LOC411472 antibody, dyn1 antibody, cgd1_580 antibody, EHI_052740 antibody, PVX_092875 antibody, BBOV_II002980 antibody, Drp1 antibody
    背景

    Description: The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.

    Aliases: DLP1, DRP1, DVLP, EMPF, VPS1, DYMPLE, HDYNIV, DYNIV-11

    分子量
    81.9kDa
    基因ID
    10059
    HGNC
    10059
    UniProt
    O00429
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