电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Dynamin 1-Like 抗体 (AA 69-213)

DNM1L 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 4E11B11 unconjugated
产品编号 ABIN1724863
发货至: 中国
  • 抗原 See all Dynamin 1-Like (DNM1L) 抗体
    Dynamin 1-Like (DNM1L)
    抗原表位
    • 23
    • 11
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 69-213
    适用
    • 50
    • 44
    • 27
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 59
    • 6
    小鼠
    克隆类型
    • 59
    • 6
    单克隆
    标记
    • 31
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Dynamin 1-Like antibody is un-conjugated
    应用范围
    • 32
    • 27
    • 17
    • 13
    • 13
    • 11
    • 9
    • 9
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    原理
    DNM1L Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human DNM1L (AA: 69-213) expressed in E. Coli.
    克隆位点
    4E11B11
    亚型
    IgG1
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Thomas, Jacobson: "Defects in mitochondrial fission protein dynamin-related protein 1 are linked to apoptotic resistance and autophagy in a lung cancer model." in: PLoS ONE, Vol. 7, Issue 9, pp. e45319, (2012) (PubMed).

    Marsboom, Toth, Ryan, Hong, Wu, Fang, Thenappan, Piao, Zhang, Pogoriler, Chen, Morrow, Weir, Rehman, Archer: "Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension." in: Circulation research, Vol. 110, Issue 11, pp. 1484-97, (2012) (PubMed).

  • 抗原
    Dynamin 1-Like (DNM1L)
    别名
    DNM1L (DNM1L 产品)
    背景

    Description: The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.

    Aliases: DLP1, DRP1, DVLP, EMPF, VPS1, DYMPLE, HDYNIV, DYNIV-11

    分子量
    81.9kDa
    基因ID
    10059
    HGNC
    10059
    UniProt
    O00429
You are here:
客服