Osteoactivin 抗体 (AA 31-260)
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- 抗原 See all Osteoactivin (GPNMB) 抗体
- Osteoactivin (GPNMB)
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抗原表位
- AA 31-260
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Osteoactivin antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human GPNMB (AA: 31-260) expressed in E. coli.
- 克隆位点
- 7C10E5
- 亚型
- IgG1
- Top Product
- Discover our top product GPNMB Primary Antibody
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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Glycoprotein transmembrane nmb: an androgen-downregulated gene attenuates cell invasion and tumorigenesis in prostate carcinoma cells." in: The Prostate, Vol. 72, Issue 13, pp. 1431-42, (2012) (PubMed).
: "GPNMB expression in uveal melanoma: a potential for targeted therapy." in: Melanoma research, Vol. 20, Issue 3, pp. 184-90, (2010) (PubMed).
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Glycoprotein transmembrane nmb: an androgen-downregulated gene attenuates cell invasion and tumorigenesis in prostate carcinoma cells." in: The Prostate, Vol. 72, Issue 13, pp. 1431-42, (2012) (PubMed).
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- 抗原
- Osteoactivin (GPNMB)
- 别名
- GPNMB (GPNMB 产品)
- 别名
- HGFIN antibody, NMB antibody, DC-HIL antibody, Dchil antibody, ipd antibody, glycoprotein nmb antibody, glycoprotein (transmembrane) nmb antibody, glycoprotein nmb L homeolog antibody, Gpnmb antibody, GPNMB antibody, gpnmb.L antibody
- 背景
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Description: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. ,
Aliases: NMB, HGFIN
- 分子量
- 64 kDa
- 基因ID
- 10457
- HGNC
- 10457
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