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Osteoactivin 抗体 (AA 31-260)

GPNMB 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 7C10E5 unconjugated
产品编号 ABIN1724859
发货至: 中国
  • 抗原 See all Osteoactivin (GPNMB) 抗体
    Osteoactivin (GPNMB)
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-260
    适用
    • 58
    • 25
    • 24
    • 7
    • 7
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    宿主
    • 46
    • 13
    小鼠
    克隆类型
    • 47
    • 12
    单克隆
    标记
    • 20
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Osteoactivin antibody is un-conjugated
    应用范围
    • 46
    • 21
    • 13
    • 13
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    原理
    GPNMB Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human GPNMB (AA: 31-260) expressed in E. Coli.
    克隆位点
    7C10E5
    亚型
    IgG1
    Top Product
    Discover our top product GPNMB Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Tsui, Chang, Feng, Chang, Juang: "Glycoprotein transmembrane nmb: an androgen-downregulated gene attenuates cell invasion and tumorigenesis in prostate carcinoma cells." in: The Prostate, Vol. 72, Issue 13, pp. 1431-42, (2012) (PubMed).

    Williams, Esmaeli, Soheili, Simantov, Gombos, Bedikian, Hwu: "GPNMB expression in uveal melanoma: a potential for targeted therapy." in: Melanoma research, Vol. 20, Issue 3, pp. 184-90, (2010) (PubMed).

  • 抗原
    Osteoactivin (GPNMB)
    别名
    GPNMB (GPNMB 产品)
    别名
    HGFIN antibody, NMB antibody, DC-HIL antibody, Dchil antibody, ipd antibody, glycoprotein nmb antibody, glycoprotein (transmembrane) nmb antibody, glycoprotein nmb L homeolog antibody, Gpnmb antibody, GPNMB antibody, gpnmb.L antibody
    背景

    Description: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

    Aliases: NMB, HGFIN

    分子量
    64kDa
    基因ID
    10457
    HGNC
    10457
    UniProt
    Q14956
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