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IL3RA 抗体 (AA 200-305)

IL3RA 适用: 人 FACS, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 8E11C5 unconjugated
产品编号 ABIN1724855
发货至: 中国
  • 抗原 See all IL3RA 抗体
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    抗原表位
    • 16
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 200-305
    适用
    • 106
    • 32
    • 3
    宿主
    • 58
    • 51
    • 3
    • 1
    小鼠
    克隆类型
    • 64
    • 48
    • 1
    单克隆
    标记
    • 45
    • 9
    • 8
    • 7
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL3RA antibody is un-conjugated
    应用范围
    • 71
    • 55
    • 14
    • 14
    • 13
    • 13
    • 11
    • 9
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
    原理
    IL3RA Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human IL3RA (AA: 200-305) expressed in E. Coli.
    克隆位点
    8E11C5
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Venkataraman, Aguhar, Kreitman, Yuan, Stetler-Stevenson: "Characteristic CD103 and CD123 expression pattern defines hairy cell leukemia: usefulness of CD123 and CD103 in the diagnosis of mature B-cell lymphoproliferative disorders." in: American journal of clinical pathology, Vol. 136, Issue 4, pp. 625-30, (2011) (PubMed).

    Yue, Fu, Wang, Li, Hu, Fu, Shao: "Expression of CD123 and CD114 on the bone marrow cells of patients with myelodysplastic syndrome." in: Chinese medical journal, Vol. 123, Issue 15, pp. 2034-7, (2010) (PubMed).

  • 抗原
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    别名
    IL3RA (IL3RA 产品)
    别名
    CD123 antibody, IL3R antibody, IL3RAY antibody, IL3RX antibody, IL3RY antibody, hIL-3Ra antibody, CDw123 antibody, SUT-1 antibody, Cyrl antibody, interleukin 3 receptor subunit alpha antibody, interleukin 3 receptor, alpha chain antibody, IL3RA antibody, Il3ra antibody
    背景

    Description: The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.



    Aliases: IL3R, CD123, IL3RX, IL3RY, IL3RAY, hIL-3Ra

    分子量
    43.3kDa
    基因ID
    3563
    HGNC
    3563
    UniProt
    P26951
    途径
    JAK/STAT Signaling
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