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FLIP 抗体 (AA 100-251)

CFLAR 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7A3D12 unconjugated
产品编号 ABIN1724850
发货至: 中国
  • 抗原 See all FLIP (CFLAR) 抗体
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    抗原表位
    • 16
    • 15
    • 15
    • 9
    • 7
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-251
    适用
    • 100
    • 66
    • 58
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 91
    • 13
    • 2
    小鼠
    克隆类型
    • 93
    • 13
    单克隆
    标记
    • 52
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FLIP antibody is un-conjugated
    应用范围
    • 95
    • 39
    • 26
    • 25
    • 20
    • 18
    • 12
    • 12
    • 12
    • 10
    • 9
    • 5
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    原理
    CFLAR Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human CFLAR (AA: 100-251) expressed in E. Coli.
    克隆位点
    7A3D12
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Bedolla, Gong, Prihoda, Yeh, Thompson, Ghosh, Kumar: "Predictive value of Sp1/Sp3/FLIP signature for prostate cancer recurrence." in: PLoS ONE, Vol. 7, Issue 9, pp. e44917, (2012) (PubMed).

    Li, Ren, Yue, Chen, Khuri, Sun: "The novel Akt inhibitor API-1 induces c-FLIP degradation and synergizes with TRAIL to augment apoptosis independent of Akt inhibition." in: Cancer prevention research (Philadelphia, Pa.), Vol. 5, Issue 4, pp. 612-20, (2012) (PubMed).

  • 抗原
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    别名
    CFLAR (CFLAR 产品)
    别名
    Clarp1 antibody, cflar antibody, CFLAR antibody, FLIP antibody, CASH antibody, CASP8AP1 antibody, CLARP antibody, Casper antibody, FLAME antibody, FLAME-1 antibody, FLAME1 antibody, I-FLICE antibody, MRIT antibody, c-FLIP antibody, c-FLIPL antibody, c-FLIPR antibody, c-FLIPS antibody, 2310024N18Rik antibody, A430105C05Rik antibody, Cash antibody, ENSMUSG00000072980 antibody, Flip antibody, Gm9845 antibody, c-Flip antibody, CASP8 and FADD-like apoptosis regulator a antibody, CASP8 and FADD like apoptosis regulator antibody, CASP8 and FADD like apoptosis regulator S homeolog antibody, CASP8 and FADD-like apoptosis regulator antibody, cflara antibody, CFLAR antibody, cflar antibody, cflar.S antibody, Cflar antibody
    背景

    Description: The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.


    Aliases: CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, c-FLIPL, c-FLIPR, c-FLIPS, CASP8AP1

    分子量
    55kDa
    基因ID
    8837
    HGNC
    8837
    UniProt
    O15519
    途径
    Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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