MCAM 抗体 (AA 84-189)
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- 抗原 See all MCAM 抗体
- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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抗原表位
- AA 84-189
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MCAM antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), ELISA
- 原理
- MCAM Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human MCAM (AA: 84-189) expressed in E. Coli.
- 克隆位点
- 6C3E6
- 亚型
- IgG1
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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CD146, a multi-functional molecule beyond adhesion." in: Cancer letters, Vol. 330, Issue 2, pp. 150-62, (2013) (PubMed).
: "The involvement of CD146 and its novel ligand Galectin-1 in apoptotic regulation of endothelial cells." in: The Journal of biological chemistry, Vol. 288, Issue 4, pp. 2571-9, (2013) (PubMed).
: "
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CD146, a multi-functional molecule beyond adhesion." in: Cancer letters, Vol. 330, Issue 2, pp. 150-62, (2013) (PubMed).
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- 抗原
- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
- 别名
- MCAM (MCAM 产品)
- 别名
- CD146 antibody, MUC18 antibody, Muc18 antibody, 1-gicerin antibody, AV025631 antibody, CD149 antibody, s-endo antibody, s-gicerin antibody, cd146 antibody, gicerin antibody, id:ibd3512 antibody, mcam antibody, MCAM antibody, melanoma cell adhesion molecule antibody, melanoma cell adhesion molecule b antibody, MCAM antibody, Mcam antibody, mcamb antibody
- 背景
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Description: The protein encoded by this gene plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
Aliases: CD146, MUC18
- 分子量
- 71.6kDa
- 基因ID
- 4162
- HGNC
- 4162
- UniProt
- P43121
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