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NG2 抗体 (AA 2247-2308)

MCSP 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7G4E5 unconjugated
产品编号 ABIN1724837
发货至: 中国
  • 抗原 See all NG2 (MCSP) 抗体
    NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
    抗原表位
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2247-2308
    适用
    • 44
    • 23
    • 17
    • 1
    宿主
    • 42
    • 13
    小鼠
    克隆类型
    • 32
    • 22
    • 1
    单克隆
    标记
    • 27
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This NG2 antibody is un-conjugated
    应用范围
    • 30
    • 20
    • 10
    • 9
    • 8
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    原理
    CSPG4 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human CSPG4 (AA: 2247-2308) expressed in E. Coli.
    克隆位点
    7G4E5
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Wang, Katayama, Wang, Yu, Favoino, Sakakura, Favole, Tsuchikawa, Silver, Watkins, Kageshita, Ferrone: "Functional characterization of an scFv-Fc antibody that immunotherapeutically targets the common cancer cell surface proteoglycan CSPG4." in: Cancer research, Vol. 71, Issue 24, pp. 7410-22, (2011) (PubMed).

    Price, Colvin Wanshura, Yang, Carlson, Xiang, Li, Ferrone, Dudek, Turley, McCarthy: "CSPG4, a potential therapeutic target, facilitates malignant progression of melanoma." in: Pigment cell & melanoma research, Vol. 24, Issue 6, pp. 1148-57, (2011) (PubMed).

  • 抗原
    NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
    别名
    CSPG4 (MCSP 产品)
    别名
    HMW-MAA antibody, MCSP antibody, MCSPG antibody, MEL-CSPG antibody, MSK16 antibody, NG2 antibody, 4732461B14Rik antibody, AN2 antibody, Ng2 antibody, HSMCSGEN1 antibody, MCS antibody, chondroitin sulfate proteoglycan 4 antibody, sperm mitochondria associated cysteine rich protein antibody, CSPG4 antibody, Cspg4 antibody, SMCP antibody
    背景

    Description: A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.

    Aliases: NG2, MCSP, MCSPG, MSK16, HMW-MAA, MEL-CSPG

    分子量
    250.0kDa
    基因ID
    1464
    HGNC
    1464
    UniProt
    Q6UVK1
    途径
    Glycosaminoglycan Metabolic Process
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