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SQSTM1 抗体 (AA 232-356)

SQSTM1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5H7E2 unconjugated
产品编号 ABIN1724836
发货至: 中国
  • 抗原 See all SQSTM1 抗体
    SQSTM1 (Sequestosome 1 (SQSTM1))
    抗原表位
    • 19
    • 17
    • 15
    • 13
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 232-356
    适用
    • 149
    • 65
    • 61
    • 18
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 126
    • 21
    • 1
    • 1
    小鼠
    克隆类型
    • 128
    • 21
    单克隆
    标记
    • 70
    • 11
    • 10
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SQSTM1 antibody is un-conjugated
    应用范围
    • 100
    • 55
    • 40
    • 36
    • 21
    • 16
    • 16
    • 15
    • 14
    • 13
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
    原理
    SQSTM1 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human SQSTM1 (AA: 232-356) expressed in E. Coli.
    克隆位点
    5H7E2
    亚型
    IgG1
    Top Product
    Discover our top product SQSTM1 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Inoue, Suzuki, Mitsuishi, Miki, Suzuki, Sugawara, Watanabe, Sakurada, Endo, Uruno, Sasano, Nakagawa, Satoh, Tanaka, Kubo, Motohashi, Yamamoto: "Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma." in: Cancer science, Vol. 103, Issue 4, pp. 760-6, (2012) (PubMed).

  • 抗原
    SQSTM1 (Sequestosome 1 (SQSTM1))
    别名
    SQSTM1 (SQSTM1 产品)
    别名
    SQSTM1 antibody, sqstm1 antibody, MGC79491 antibody, A170 antibody, OSIL antibody, PDB3 antibody, ZIP3 antibody, p60 antibody, p62 antibody, p62B antibody, OSF-6 antibody, Osi antibody, STAP antibody, ZIP antibody, sb:cb621 antibody, zgc:85784 antibody, sequestosome 1 antibody, sequestosome 1 L homeolog antibody, SQSTM1 antibody, sqstm1 antibody, Sqstm1 antibody, sqstm1.L antibody
    背景

    Description: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

    Aliases: p60, p62, A170, OSIL, PDB3, ZIP3, p62B

    分子量
    47.7kDa
    基因ID
    8878
    HGNC
    8878
    UniProt
    Q13501
    途径
    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
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