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MAPK14 抗体 (AA 299-360)

Name: MAPK14 抗体 (AA 299-360)
Brand: antibodies-online
SKU: ABIN1724830
Availability: OutOfStock

MAPK14 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 8G4D11 unconjugated

Western blot analysis using MAPK14 mouse mAb against HeLa (1), NIH/3T3 (2), Jurkat (3), Raw264. (MAPK14 抗体 (AA 299-360))

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (MAPK14 抗体 (AA 299-360))

ELISA

Flow cytometric analysis of HeLa cells using MAPK14 mouse mAb (green) and negative control (red). (MAPK14 抗体 (AA 299-360))

FACS

Immunofluorescence analysis of HeLa cells using MAPK14 mouse mAb (green). (MAPK14 抗体 (AA 299-360))

Western blot analysis using MAPK14 mAb against human MAPK14 recombinant protein. (MAPK14 抗体 (AA 299-360))

Western blot analysis using MAPK14 mAb against HEK293 (1) and MAPK14 (AA: 299-360)-hIgGFc transfected HEK293 (2) cell lysate. (MAPK14 抗体 (AA 299-360))

Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using MAPK14 mouse mAb with DAB staining. (MAPK14 抗体 (AA 299-360))

IHC

Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using MAPK14 mouse mAb with DAB staining. (MAPK14 抗体 (AA 299-360))

IHC

8 images

(2 references)

产品编号 ABIN1724830

发货至: 中国

Datasheet as PDF

抗原 See all MAPK14 抗体

MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))
抗原表位
40

33

18

16

16

12

12

10

8

7

6

6

6

6

6

5

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 299-360
适用
251

161

141

28

24

23

16

14

12

12

9

7

6

3

3

3

3

1

1

1

1

1
人
宿主
222

30

2

1
小鼠
Compatible Secondaries
克隆类型
215

42
单克隆
标记
132

15

14

11

10

8

4

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

1

1
This MAPK14 antibody is un-conjugated
应用范围
198

111

74

48

43

42

37

29

28

20

10

10

5

5

4

2

2

1

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

原理

MAPK14 Antibody

纯化方法

Purified antibody

免疫原

Purified recombinant fragment of human MAPK14 (AA: 299-360) expressed in E. Coli.

克隆位点

8G4D11

亚型

IgG1

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anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 141-240) antibody
MAPK14 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IHC (p), FACS, ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 19-279) antibody
MAPK14 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (Ser272) antibody
MAPK14 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 260-360) antibody
MAPK14 适用: 人 WB, ELISA, IP, IHC (p), PLA 宿主: 小鼠 Monoclonal 3D5 unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 299-360) antibody
MAPK14 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 10B11C8 unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 295-324), (C-Term) antibody
MAPK14 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB2723 unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) antibody
MAPK14 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (C-Term) antibody
MAPK14 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 299-360) antibody
MAPK14 适用: 人, 小鼠 WB, ELISA, IHC, IF/ICC, FACS 宿主: 小鼠 Monoclonal unconjugated

应用备注

ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/75

限制

仅限研究用
状态

Liquid

缓冲液

Purified antibody in PBS with 0.05 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Li, Zheng, Li, Ma: "Unfractionated heparin inhibits lipopolysaccharide-induced inflammatory response through blocking p38 MAPK and NF-?B activation on endothelial cell." in: Cytokine, Vol. 60, Issue 1, pp. 114-21, (2012) (PubMed).

Chung, Tang, Sun, Chou, Yeh, Yu, Sun: "Galectin-1 promotes lung cancer progression and chemoresistance by upregulating p38 MAPK, ERK, and cyclooxygenase-2." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 15, pp. 4037-47, (2012) (PubMed).
抗原

MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

别名

MAPK14 (MAPK14 产品)

别名

CSBP antibody, CSBP1 antibody, CSBP2 antibody, CSPB1 antibody, EXIP antibody, Mxi2 antibody, PRKM14 antibody, PRKM15 antibody, RK antibody, SAPK2A antibody, p38 antibody, p38ALPHA antibody, CRK1 antibody, Csbp1 antibody, Csbp2 antibody, Exip antibody, Hog antibody, Prkm14 antibody, Prkm15 antibody, Sapk2A antibody, p38Hog antibody, p38alpha antibody, p38b antibody, zp38b antibody, MAPK14 antibody, 186F5S antibody, BG:DS00797.3 antibody, CG7393 antibody, D-p38 antibody, D-p38 MAPK antibody, D-p38b antibody, Dm p38b antibody, Dmel\\CG7393 antibody, Dmp38b antibody, Dp38 antibody, Dp38b antibody, ESTS:186F5S antibody, Mpk34C antibody, anon-sts23 antibody, dp38b antibody, p38 MAPK antibody, p38 beta antibody, p38B antibody, p38Kb antibody, p38beta antibody, Crk1 antibody, p38-alpha antibody, p38MAPK antibody, p38a antibody, csbp antibody, mapk14a antibody, mxi2 antibody, sapk2 antibody, sapk2a antibody, AP22.98 antibody, AP22_98 antibody, ATMPK14 antibody, mitogen-activated protein kinase 14 antibody, SAPK2a antibody, MAP kinase 14A antibody, MAP kinase p38a antibody, MAPK 14A antibody, fk28c03 antibody, hm:zeh1243 antibody, wu:fk28c03 antibody, zp38a antibody, P38C-CRK antibody, mitogen-activated protein kinase 14 antibody, mitogen activated protein kinase 14 antibody, mitogen-activated protein kinase 14b antibody, p38b MAP kinase antibody, mitogen-activated protein kinase 14 S homeolog antibody, mitogen-activated protein kinase 14a antibody, CRK proto-oncogene, adaptor protein antibody, MAPK14 antibody, Mapk14 antibody, mapk14b antibody, p38b antibody, mapk14.S antibody, MPK14 antibody, mapk14a antibody, CRK antibody

背景

Description: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Aliases: RK, p38, CSBP, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, SAPK2A, p38ALPHA

分子量

41.3kDa

基因ID

1432

HGNC

1432

UniProt

Q16539

途径

MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins