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KLF1 抗体 (AA 208-362)

KLF1 适用: 人 ELISA, WB, IHC, FACS 宿主: 小鼠 Monoclonal 1B6A3 unconjugated
产品编号 ABIN1724828
发货至: 中国
  • 抗原 See all KLF1 抗体
    KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))
    抗原表位
    • 9
    • 9
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 208-362
    适用
    • 45
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    宿主
    • 35
    • 10
    • 1
    小鼠
    克隆类型
    • 37
    • 10
    单克隆
    标记
    • 26
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KLF1 antibody is un-conjugated
    应用范围
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human KLF1 (AA: 208-362) expressed in E. coli.
    克隆位点
    1B6A3
    亚型
    IgG1
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Alhashem, Vinjamur, Basu, Klingmüller, Gaensler, Lloyd: "Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding." in: The Journal of biological chemistry, Vol. 286, Issue 28, pp. 24819-27, (2011) (PubMed).

    Zhou, Liu, Sun, Pawlik, Townes: "KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching." in: Nature genetics, Vol. 42, Issue 9, pp. 742-4, (2010) (PubMed).

  • 抗原
    KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))
    别名
    KLF1 (KLF1 产品)
    别名
    KLF1 antibody, EKLF antibody, HBFQTL6 antibody, INLU antibody, Eklf antibody, Nan antibody, Kruppel-like factor 1 (erythroid) antibody, Kruppel like factor 1 antibody, KLF-4 antibody, KLF1 antibody, Klf1 antibody
    背景

    Description: This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. , ,

    Aliases: EKLF, INLU, HBFQTL6

    分子量
    38.2 kDa
    基因ID
    10661
    HGNC
    10661
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