Integrin Alpha2b 抗体 (AA 45-149)
-
- 抗原 See all Integrin Alpha2b (CD41) 抗体
- Integrin Alpha2b (CD41)
-
抗原表位
- AA 45-149
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This Integrin Alpha2b antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)
- 原理
- ITGA2B Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human ITGA2B (AA: 45-149) expressed in E. Coli.
- 克隆位点
- 2E10C9
- 亚型
- IgG1
-
-
- 应用备注
-
ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
Novel and recurrent mutations of ITGA2B and ITGB3 genes in Korean patients with Glanzmann thrombasthenia." in: Pediatric blood & cancer, Vol. 59, Issue 2, pp. 335-8, (2012) (PubMed).
: "Glanzmann thrombasthenia: a review of ITGA2B and ITGB3 defects with emphasis on variants, phenotypic variability, and mouse models." in: Blood, Vol. 118, Issue 23, pp. 5996-6005, (2011) (PubMed).
: "
-
Novel and recurrent mutations of ITGA2B and ITGB3 genes in Korean patients with Glanzmann thrombasthenia." in: Pediatric blood & cancer, Vol. 59, Issue 2, pp. 335-8, (2012) (PubMed).
-
- 抗原
- Integrin Alpha2b (CD41)
- 别名
- ITGA2B (CD41 产品)
- 背景
-
Description: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Aliases: GT, GTA, CD41, GP2B, HPA3, CD41B, GPIIb, BDPLT2
- 分子量
- 113.4kDa
- 基因ID
- 3674
- HGNC
- 3674
- UniProt
- P08514
- 途径
- Integrin Complex
-