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TP53BP1 抗体 (AA 574-773)

TP53BP1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 6B3E10 unconjugated
产品编号 ABIN1724820
发货至: 中国
  • 抗原 See all TP53BP1 抗体
    TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
    抗原表位
    • 32
    • 21
    • 15
    • 11
    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
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    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 574-773
    适用
    • 103
    • 63
    • 61
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 108
    • 7
    • 2
    • 1
    小鼠
    克隆类型
    • 102
    • 16
    单克隆
    标记
    • 57
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TP53BP1 antibody is un-conjugated
    应用范围
    • 43
    • 29
    • 27
    • 27
    • 25
    • 18
    • 17
    • 12
    • 10
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
    原理
    TP53BP1 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human TP53BP1 (AA: 574-773) expressed in E. Coli.
    克隆位点
    6B3E10
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Nakada, Yonamine, Matsuo: "RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1." in: Cancer research, Vol. 72, Issue 19, pp. 4974-83, (2012) (PubMed).

    Mok, Henderson: "The in vivo dynamic interplay of MDC1 and 53BP1 at DNA damage-induced nuclear foci." in: The international journal of biochemistry & cell biology, Vol. 44, Issue 9, pp. 1398-409, (2012) (PubMed).

  • 抗原
    TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
    别名
    TP53BP1 (TP53BP1 产品)
    别名
    TP53BP1 antibody, MGC160112 antibody, 53BP1 antibody, Tp53bp1 antibody, m53BP1 antibody, p202 antibody, Trp53bp1 antibody, tumor protein p53 binding protein 1 antibody, tumor suppressor p53-binding protein 1 antibody, tumor protein p53 binding protein 1 (predicted), 5 prime antibody, transformation related protein 53 binding protein 1 antibody, TP53BP1 antibody, tp53bp1 antibody, LOC100550605 antibody, Trp53bp1 antibody, Tp53bp1 antibody
    背景

    Description: T protein p53 binding protein 1 may have a role in checkpoint signaling during mitosis,enhance TP53-mediated transcriptional activation and play a role in the response to DNA damage.

    Aliases: p202, 53BP1

    分子量
    213.6kDa
    基因ID
    7158
    HGNC
    7158
    UniProt
    Q12888
    途径
    DNA Damage Repair
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