CD33 抗体 (AA 15-237)
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- 抗原 See all CD33 抗体
- CD33
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抗原表位
- AA 15-237
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD33 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)
- 原理
- CD33 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human CD33 (AA: 15-237) expressed in E. Coli.
- 克隆位点
- 2C6B7
- 亚型
- IgG1
- Top Product
- Discover our top product CD33 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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The prevalence of CD33 and MS4A6A variant in Chinese Han population with Alzheimer's disease." in: Human genetics, Vol. 131, Issue 7, pp. 1245-9, (2012) (PubMed).
: "A single-chain triplebody with specificity for CD19 and CD33 mediates effective lysis of mixed lineage leukemia cells by dual targeting." in: mAbs, Vol. 3, Issue 1, pp. 21-30, (2011) (PubMed).
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The prevalence of CD33 and MS4A6A variant in Chinese Han population with Alzheimer's disease." in: Human genetics, Vol. 131, Issue 7, pp. 1245-9, (2012) (PubMed).
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- 抗原
- CD33
- 别名
- CD33 (CD33 产品)
- 别名
- SIGLEC-3 antibody, SIGLEC3 antibody, p67 antibody, Siglec-3 antibody, gp67 antibody, CD33 molecule antibody, CD33 antigen antibody, CD33 antibody, Cd33 antibody
- 背景
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Description: The protein encoded by this gene belongs to putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro) and CD33 plays potential key roles in the pathogenesis of Alzheimer's disease (AD)
Aliases: p67, SIGLEC3, SIGLEC-3
- 分子量
- 39.8kDa
- 基因ID
- 945
- HGNC
- 945
- UniProt
- P20138
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