Integrin beta 4 抗体 (AA 1619-1822)
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- 抗原 See all Integrin beta 4 (ITGB4) 抗体
- Integrin beta 4 (ITGB4)
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抗原表位
- AA 1619-1822
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Integrin beta 4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human ITGB4 (AA: 1619-1822) expressed in E. coli.
- 克隆位点
- 10B10D5
- 亚型
- IgG1
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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Downregulation of integrin β4 decreases the ability of airway epithelial cells to present antigens." in: PLoS ONE, Vol. 7, Issue 4, pp. e32060, (2012) (PubMed).
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Downregulation of integrin β4 decreases the ability of airway epithelial cells to present antigens." in: PLoS ONE, Vol. 7, Issue 4, pp. e32060, (2012) (PubMed).
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- 抗原
- Integrin beta 4 (ITGB4)
- 别名
- ITGB4 (ITGB4 产品)
- 别名
- AA407042 antibody, C230078O20 antibody, CD104 antibody, integrin subunit beta 4 antibody, integrin beta 4 antibody, ITGB4 antibody, Itgb4 antibody
- 背景
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Description: Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. , , ,
Aliases: CD104
- 分子量
- 202 kDa
- 基因ID
- 3691
- HGNC
- 3691
- 途径
- Integrin Complex
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