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PDE1B 抗体 (AA 370-536)

PDE1B 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5C4A3 unconjugated
产品编号 ABIN1724781
发货至: 中国
  • 抗原 See all PDE1B 抗体
    PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))
    抗原表位
    • 14
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    AA 370-536
    适用
    • 45
    • 28
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 46
    • 9
    小鼠
    克隆类型
    • 46
    • 9
    单克隆
    标记
    • 24
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDE1B antibody is un-conjugated
    应用范围
    • 42
    • 34
    • 20
    • 10
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    原理
    PDE1B Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human PDE1B (AA: 370-536 ) expressed in E. Coli.
    克隆位点
    5C4A3
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Vandeput, Wolda, Krall, Hambleton, Uher, McCaw, Radwanski, Florio, Movsesian: "Cyclic nucleotide phosphodiesterase PDE1C1 in human cardiac myocytes." in: The Journal of biological chemistry, Vol. 282, Issue 45, pp. 32749-57, (2007) (PubMed).

  • 抗原
    PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))
    别名
    PDE1B (PDE1B 产品)
    别名
    63kDa antibody, Pde1b1 antibody, PDE1B1 antibody, PDES1B antibody, Aop2 antibody, phosphodiesterase 1B, Ca2+-calmodulin dependent antibody, phosphodiesterase 1B antibody, Pde1b antibody, PDE1B antibody
    背景

    Description: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    Aliases: PDE1B1, PDES1B

    分子量
    61.4kDa
    基因ID
    5153
    HGNC
    5153
    UniProt
    Q01064
    途径
    Neurotrophin Signaling Pathway, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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