Cadherin 5 抗体 (AA 29-223)
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- 抗原 See all Cadherin 5 (CDH5) 抗体
- Cadherin 5 (CDH5)
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抗原表位
- AA 29-223
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Cadherin 5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- 原理
- CDH5 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human CDH5 (AA: 29-223 ) expressed in E. Coli.
- 克隆位点
- 3D5C7
- 亚型
- IgG1
- Top Product
- Discover our top product CDH5 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Dentin matrix protein 1 induces membrane expression of VE-cadherin on endothelial cells and inhibits VEGF-induced angiogenesis by blocking VEGFR-2 phosphorylation." in: Blood, Vol. 117, Issue 8, pp. 2515-26, (2011) (PubMed).
: "Andes virus disrupts the endothelial cell barrier by induction of vascular endothelial growth factor and downregulation of VE-cadherin." in: Journal of virology, Vol. 84, Issue 21, pp. 11227-34, (2010) (PubMed).
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Dentin matrix protein 1 induces membrane expression of VE-cadherin on endothelial cells and inhibits VEGF-induced angiogenesis by blocking VEGFR-2 phosphorylation." in: Blood, Vol. 117, Issue 8, pp. 2515-26, (2011) (PubMed).
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- 抗原
- Cadherin 5 (CDH5)
- 别名
- CDH5 (CDH5 产品)
- 别名
- 7B4 antibody, AA408225 antibody, Cd144 antibody, VE-Cad antibody, VECD antibody, VEcad antibody, Vec antibody, wu:fc88a07 antibody, CD144 antibody, cadherin-5 antibody, cadherin 5 antibody, CDH5 antibody, Cdh5 antibody, cdh5 antibody
- 背景
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Description: This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined.
Aliases: 7B4, CD144
- 分子量
- 87.5kDa
- 基因ID
- 1003
- HGNC
- 1003
- UniProt
- P33151
- 途径
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
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