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Cadherin 5 抗体 (AA 29-223)

CDH5 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3D5C7 unconjugated
产品编号 ABIN1724748
发货至: 中国
  • 抗原 See all Cadherin 5 (CDH5) 抗体
    Cadherin 5 (CDH5)
    抗原表位
    • 16
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-223
    适用
    • 99
    • 64
    • 42
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 87
    • 24
    • 6
    • 1
    小鼠
    克隆类型
    • 86
    • 32
    单克隆
    标记
    • 69
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cadherin 5 antibody is un-conjugated
    应用范围
    • 84
    • 41
    • 37
    • 36
    • 18
    • 16
    • 14
    • 14
    • 13
    • 11
    • 10
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    原理
    CDH5 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human CDH5 (AA: 29-223 ) expressed in E. Coli.
    克隆位点
    3D5C7
    亚型
    IgG1
    Top Product
    Discover our top product CDH5 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Pirotte, Lamour, Lambert, Alvarez Gonzalez, Ormenese, Noël, Mottet, Castronovo, Bellahcène: "Dentin matrix protein 1 induces membrane expression of VE-cadherin on endothelial cells and inhibits VEGF-induced angiogenesis by blocking VEGFR-2 phosphorylation." in: Blood, Vol. 117, Issue 8, pp. 2515-26, (2011) (PubMed).

    Shrivastava-Ranjan, Rollin, Spiropoulou: "Andes virus disrupts the endothelial cell barrier by induction of vascular endothelial growth factor and downregulation of VE-cadherin." in: Journal of virology, Vol. 84, Issue 21, pp. 11227-34, (2010) (PubMed).

  • 抗原
    Cadherin 5 (CDH5)
    别名
    CDH5 (CDH5 产品)
    别名
    7B4 antibody, AA408225 antibody, Cd144 antibody, VE-Cad antibody, VECD antibody, VEcad antibody, Vec antibody, wu:fc88a07 antibody, CD144 antibody, cadherin-5 antibody, cadherin 5 antibody, CDH5 antibody, Cdh5 antibody, cdh5 antibody
    背景

    Description: This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined.

    Aliases: 7B4, CD144

    分子量
    87.5kDa
    基因ID
    1003
    HGNC
    1003
    UniProt
    P33151
    途径
    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
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