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BMPR1A 抗体 (AA 179-378)

BMPR1A 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 4B7B2 unconjugated
产品编号 ABIN1724745
发货至: 中国
  • 抗原 See all BMPR1A 抗体
    BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))
    抗原表位
    • 16
    • 10
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 179-378
    适用
    • 74
    • 51
    • 32
    • 1
    宿主
    • 90
    • 6
    • 1
    小鼠
    克隆类型
    • 92
    • 5
    单克隆
    标记
    • 42
    • 9
    • 8
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BMPR1A antibody is un-conjugated
    应用范围
    • 86
    • 57
    • 32
    • 23
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    原理
    BMPR1A Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human BMPR1A (AA: 179-378 ) expressed in E. Coli.
    克隆位点
    4B7B2
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Nickel, Kotzsch, Sebald, Mueller: "Purification, crystallization and preliminary data analysis of the ligand-receptor complex of the growth and differentiation factor 5 variant R57A (GDF5R57A) and BMP receptor IA (BRIA)." in: Acta crystallographica. Section F, Structural biology and crystallization communications, Vol. 67, Issue Pt 5, pp. 551-5, (2011) (PubMed).

    Nieminen, Abdel-Rahman, Ristimäki, Lappalainen, Lahermo, Mecklin, Järvinen, Peltomäki: "BMPR1A mutations in hereditary nonpolyposis colorectal cancer without mismatch repair deficiency." in: Gastroenterology, Vol. 141, Issue 1, pp. e23-6, (2011) (PubMed).

  • 抗原
    BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))
    别名
    BMPR1A (BMPR1A 产品)
    别名
    10q23del antibody, ACVRLK3 antibody, ALK3 antibody, CD292 antibody, SKR5 antibody, 1110037I22Rik antibody, AU045487 antibody, BMPR-IA antibody, Bmpr antibody, BMPR-1 antibody, BRK-1 antibody, BMPR1A antibody, acvrlk3 antibody, alk-3 antibody, alk3 antibody, cd292 antibody, skr5 antibody, BR1a antibody, alk3tr antibody, bmpr1a antibody, zgc:136731 antibody, wu:fe05b06 antibody, wu:fe06e10 antibody, zgc:92227 antibody, bone morphogenetic protein receptor type 1A antibody, bone morphogenetic protein receptor, type 1A antibody, bone morphogenetic protein receptor type 1A S homeolog antibody, bone morphogenetic protein receptor, type IAa antibody, bone morphogenetic protein receptor, type IAb antibody, BMPR1A antibody, Bmpr1a antibody, bmpr1a antibody, bmpr1a.S antibody, bmpr1aa antibody, bmpr1ab antibody
    背景

    Description: The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

    Aliases: ALK3, SKR5, CD292, ACVRLK3, 10q23del

    分子量
    60kDa
    基因ID
    657
    HGNC
    657
    UniProt
    P36894
    途径
    Stem Cell Maintenance
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